Patients with dose-limiting adverse reactions caused by amlodipine or valsartan monotherapy can switch to this product, and use a single component in combination with another component at a lower dose to achieve the effect of controlling blood pressure.
Alternative therapy: For the convenience of administration, patients who receive amlodipine combined with valsartan can switch to the same dose of this product for treatment. For information about stopping using β -receptor antagonists, please refer to the precautions. Both amlodipine and valsartan can be taken with food or on an empty stomach. It is recommended to take this product with water.
Usage and dosage:
Amlodipine 1 day 1 time 2.5- 10 mg is effective in treating hypertension, while the effective dose of valsartan is 80-320 mg. In the clinical trial of valsartan and amlodipine tablets, the antihypertensive effect increased with the increase of dose when amlodipine was 5-1 0 mg and valsartan was 80-320 mg.
The adverse reactions of valsartan are usually unrelated to the dose. The adverse reactions of amlodipine are both dose-dependent (mainly peripheral edema) and dose-independent, and the former is more common than the latter. Patients whose blood pressure cannot be completely controlled by a single drug can switch to this product.
Refer to the above content: Baidu Encyclopedia-Valsartan Amlodipine