He has successively undertaken national and provincial-level projects 12, including 2 national natural funds, published more than 0 academic papers 100, 7 were included by ISTP, and 7 were edited or edited. Presided over or participated in the research and development of preparations in two hospitals. One is Yigu Capsule, a pure Chinese medicine compound preparation, with the approval number of (98) Sui Wei Yi Tong (its)No. C- 178, which is used to prevent and treat osteoporosis, and applied for a patent 1 piece; The second is Yishou Tiaozhi Tablet, with approval number (98): Suiwei Yitong (its)No. C- 187, which is used to prevent and treat hyperlipidemia and diabetes, and has achieved good social and economic benefits. Six doctoral students and 34 master students have been trained; At present, there are 3 doctoral students and 3 master students 10. 1. Project Leader of Neuro-skeletal Signal Pathway and Intervention of Traditional Chinese Medicine on Osteoporosis Model Rats of National Natural Science Foundation
2. The effect and mechanism of kidney-tonifying herbs on osteogenic differentiation of bone marrow mesenchymal stem cells in osteoporosis rats.
3. Study on Differentiation Characteristics of Bone Marrow Mesenchymal Stem Cells in Kidney Deficiency Model Rats: Head of state administration of traditional chinese medicine Traditional Chinese Medicine Scientific Research Project.
4. Osteogenic differentiation of bone marrow mesenchymal stem cells in osteoporotic rats and intervention effect of Chinese herbs for tonifying kidney: leader of key project of Guangdong Natural Science Foundation.
5. Research on the Screening Platform of Anti-osteoporosis Chinese Medicine for Promoting Bone Differentiation of Bone Marrow Mesenchymal Stem Cells: Director of Guangdong Social Development Planning Bureau.
6. Study on the development and application of Yigu Capsule, a Chinese traditional medicine compound for preventing and treating osteoporosis.
7. Pre-clinical study of Yushu soft capsule, an antidepressant Chinese medicine. Head of Guangzhou Science and Technology Plan
8. The new drug development and research of Yigu Capsule was funded by Guangzhou Jingxiutang (Pharmaceutical) Co., Ltd., with a total investment of 4.5 million yuan, including 6.5438+0.5 million yuan for pre-clinical research and 3 million yuan for clinical research. Head 1. Yang Li, Zhang Ronghua, Cai Yu, Huang Feng. Effects of ovariectomy on biological characteristics of bone marrow mesenchymal stem cells in SD rats [J]. China Journal of Pathophysiology, 20 10/0,26 (7):1249-1254.
2. Li Bo, Zhang Ronghua. Research Progress on Deficiency Syndrome of Integrative Medicine [J]. China Journal of Integrative Medicine, 20 10, 30 (5): 557-560.
3. Wang Tingchun, Wang, Ma,. Effect of Xinmaikang Capsule on Acute Myocardial Ischemia in Coronary Artery Ligation Model Dogs [J]. Chinese Herbal Medicine, 2009,32 (11):1715-1768.
4. Wang Tingchun, Zhang Ronghua. Clinical Study on Liu 'an Capsule in Adjuvant Treatment of Non-small Cell Lung Cancer with Qi Deficiency and Phlegm Stasis [J]. Chinese Patent Medicine, 2009,31(5): 669-673.
5. Bian Wei, Zhang Ronghua, Lin Qiang and Sun Hong. Pathogenesis and treatment of polycystic ovary syndrome [J]. New Chinese Medicine, 2009,41(5): 5-6.
6. Zhang Ronghua, Li Bo. Connotation and academic viewpoint of syndrome essence [J]. China Journal of Integrated Traditional Chinese and Western Medicine, 2009,29 (4): 375-378.
7. Li Bo, Zhang Ronghua. Modern research on treating coronary heart disease with traditional Chinese medicine [J]. New Chinese Medicine, 2008,40 (6): 5-6
8. Fu Shuping, Zhang Ronghua, Xu Liqun. Effect of TNF-α on osteoblast apoptosis in * * * education system and protective effect of serum containing Yigu capsule [J]. China Journal of Pathophysiology, 2008,24 (5): 945–949.
9. Li Bo, Zhang Ronghua. Effect of Yigu Capsule on the Expression of cbfα- 1mRNA in Ovariectomized Osteoporosis Rats [J]. China Journal of Pathophysiology, 2008,24 (4): 759-762.
10. Zhang Ronghua, MC Jin. Theory that kidney governs bone marrow formation and bone differentiation of bone marrow mesenchymal stem cells [J]. journal of traditional chinese medicine, 2006; 47( 10):730-732
1 1. Zhang Ronghua, Xu Liqun, Fu Shuping, Yang Li. Effect of serum containing Yigu capsule on osteoblasts in education system [J]. Chinese Herbal Medicine, 2006; 29(7):695-697
12. Fu Shuping, Zhang Ronghua, Xu Liqun. Effects of serum containing Yigu Capsule on proliferation, ALP activity and IL- 1 1 mRNA expression of osteoblasts in * * * education system of rats [J]. China Journal of Pathophysiology, 2006; 22(6): 1 17 1- 1 173
13. Zhang Ronghua, Xu Liqun, Fu Shuping, Yang Li. Effect of serum containing Yigu capsule on osteoclast activity and apoptosis in * * * education system [J]. China Journal of Pathophysiology, 2006; 22(5): 100 1- 1004
14. Zhang Ronghua, Peng Keping, Zhu Xiaofeng, Cai Yu, Huang Feng. Effect of serum containing Yigu capsule on the expression of estrogen receptor mRNA and protein in rat osteoblasts [J]. China Journal of Integrated Traditional Chinese and Western Medicine, 2005; 25(4):333-337
15. Zhang Ronghua, Yang Li, Zhu Xiaofeng, Cai Yu, Huang Feng. Effect of Yigu Capsule on TGF-β 1mRNA expression in bone tissue of ovariectomized osteoporosis rats [J]. Chinese Herbal Medicine, 2005; 28(4):3 12-3 15
16. Hou Li, Zhang Ronghua, Yang Li, Zhu Xiaofeng, Cai Yu, Huang Feng. Effect of Yigu Capsule on Bone Morphology and Serum TNF-α Level in Osteoporosis Model Rats [J]. China Pharmacy, 2005; 16(8):577-578
17. Zhang Ronghua, Peng Keping, Zhu Xiaofeng, Cai Yu, Huang Feng. Effect of serum containing Yigu capsule on the expression of IL-6 mRNA and protein in rat osteoblasts [J]. China Journal of Pathophysiology, 2005; 2 1(3):584-587
18. Lu Daxiang,,, Qi. 265438+the development direction of integrated traditional Chinese and western medicine research in the 20th century [J]. China Journal of Pathophysiology, 2005; 2 1(8): 1657- 1657