Fatty liver is a patent for fat people. Thin people can eat and drink safely as long as they are not overweight and will not get fatty liver.
Rumors:
Fatty liver often patronizes obese and overweight patients. However, thin people will get fatty liver, fatty liver is not the patent of fat people!
Common causes of fatty liver.
The liver is an important place for fat metabolism. Under some pathological conditions, if there are too many fat sources or fat metabolism is disordered, a large number of fat droplets (mainly triglycerides) will accumulate in liver cells, which will lead to fatty degeneration. Fatty liver can be diagnosed when more than 5% of hepatocytes have steatosis. Clinically, fatty liver can be divided into alcoholic fatty liver, nonalcoholic fatty liver and special fatty liver according to the etiology.
With the development of economy and the change of lifestyle, the incidence of fatty liver in China has risen rapidly, and the prevalence rate has reached 12.5-35.4%. Fatty liver has replaced viral hepatitis as the largest chronic liver disease in China. Obesity and metabolic syndrome caused by obesity (obesity, hypertension, hyperlipidemia, hyperglycemia, hyperuricemia, etc.). ) is the primary cause of fatty liver and abnormal liver enzyme indexes. With the increasing prevalence of obesity and diabetes, the prevalence rate of adult nonalcoholic fatty liver disease (NAFLD) in China has reached more than 25%, which means that there are 5 patients with nonalcoholic fatty liver disease in every 20 people, and about 1 of these 5 patients will develop into more serious steatohepatitis.
Alcoholic fatty liver is also a problem that cannot be ignored, and the proportion of inpatients with liver disease is increasing year by year. The severity of liver injury is closely related to the amount and duration of drinking.
Generally speaking, the main reasons for the rapid growth of fatty liver are obesity, diabetes and excessive drinking.
2. Why do thin people get fatty liver?
Thin people suffering from fatty liver are generally seen in the following three situations:
The first situation is found in thin people who are malnourished due to dieting or other reasons. Dieting will lead to insufficient nutrition, insufficient heat source and increased heat production from fat decomposition; Long-term starvation and hypoglycemia stimulate sympathetic hyperfunction, aggravate lipolysis and increase fatty acid production; Malnutrition leads to hypoproteinemia and lack of apolipoprotein, so that a large number of fatty acids in the liver can not be transported to the blood by apolipoprotein, and fatty liver occurs.
The second situation is seen in thin people. They don't like sports, but they like to drink drinks or honey and eat sweet fruits. These foods contain a lot of fructose. Fructose is a monosaccharide, which is easily absorbed by human body and has a high sweetness (1.6 times sucrose). Because fructose is not metabolized by the pancreas, compared with glucose, it does not stimulate the increase of insulin and has little effect on blood sugar. It was once advertised as "good sugar", but this is not the case.
The harm of fructose to the body mainly lies in that it can be used as a raw material to synthesize fat, which can be directly stored into fat through the liver, and then trigger a series of biochemical reactions, such as increased triglyceride, increased insulin resistance, fatty liver and so on. Generally speaking, the sugar content in food is very complicated, which needs to be carefully digested by the body and then absorbed and utilized. Fructose can be directly used to accumulate fat without digestion. A study on healthy men showed that the high fructose diet increased fatty acid synthesis in the liver of the study population by 6 times, reduced the sensitivity to insulin, and the blood lipid level was abnormal, which made them more prone to abdominal obesity and increased the risk of other metabolic diseases, including fatty liver and diabetes. In this case, even if the patient has fatty liver, the weight is not necessarily overweight.
The third situation is found in patients who use certain drugs, are infected with certain viruses and have certain hereditary metabolic liver diseases. Long-term use of some drugs that have side effects on the liver may lead to fatty liver, such as common hormone drugs, arrhythmia drugs such as amiodarone, antiepileptic drugs such as sodium valproate, and antitumor drugs such as methotrexate; In addition, hepatitis C virus infection with genotype 3 may also manifest as fatty liver in the early stage; There are also some autoimmune liver diseases and hereditary metabolic liver diseases, such as hepatolenticular degeneration, which also show fatty degeneration of liver cells. Fatty liver caused by these conditions is neither fat nor thin.
It can be seen that fatty liver is not a patent for fat people. If thin people eat and drink, or lose weight unscientific, malnutrition and so on. Fatty liver can still happen.
Rumor expert: Wang Fang, director and chief physician of the Second Department of Hepatology, Shenzhen Third People's Hospital.
Expert: Yang Binghui, former dean and professor of Zhongshan Hospital affiliated to Fudan University.