Disease (PD) is a common neurodegenerative disease, which is common in the elderly. The average age of onset is about 60 years old, and Parkinson's disease is rare among young people under 40 years old. The prevalence rate of PD in people over 65 years old in China is about 1.7%. Most patients with Parkinson's disease are sporadic cases, and less than 10% patients have family history. The main pathological change of Parkinson's disease is dopamine in substantia nigra of midbrain,
DA) can make neurons degenerate and die, leading to a significant decrease in the content of DA in striatum, thus leading to diseases. The exact cause of this pathological change is not clear. Genetic factors, environmental factors, aging and oxidative stress may all participate in the degenerative death process of PD dopaminergic neurons.
Parkinson's disease is not a patent for the elderly. In recent years, the proportion of middle-aged people suffering from Parkinson's disease has gradually increased. Jiao Tao and Jiao Fei, the youngest patients with Parkinson's disease in Henan, became ill at the age of 6 and 9 respectively, which is also a starting point for the treatment of juvenile Parkinson's disease in China.