Professor Qu Guirong of Henan Normal University led the research group to develop a series of new nucleoside production processes, which won the second prize of the National Science and Technology Progress Award, and jointly developed and industrially produced 5 nucleoside products such as adenosine, cytidine and uridine with Xinxiang Tuoxin Biochemical Technology Co., Ltd. These products are reagents for genetic engineering research and the main raw materials for the production of anticancer, antiviral and anti-AIDS drugs, which broke Japan's monopoly on nucleoside products in the international market.
Qu Guirong, a 58-year-old professor at the School of Chemistry and Environmental Sciences of Henan Normal University, had a particularly happy Spring Festival this year!
On January 8th, Professor Qu Guirong went to Beijing to receive the second prize of the National Science and Technology Progress Award. During the Spring Festival, she also received three manuscripts: Organic Chemistry, the top international chemical magazine, adopted her two basic research papers on the synthesis of nucleoside compounds at one time; Another related paper will also be published by the international SCI source journal Green Chemistry. This indicates that the basic research on the synthesis of nucleoside compounds in China, represented by the research group of Qu Guirong Project, has been at the leading level in the world.
"Nucleoside is the structural fragment of RNA in human body, animals and plants, while deoxynucleoside is the structural fragment of DNA in human body, animals and plants. They are both nucleoside compounds." In a recent interview, Professor Qu told reporters that nucleosides are small biological molecules that can be used to repair damaged genes. After the substituted nucleoside enters the human body, it is embedded into the main chains of RNA and DNA of various lesions such as viruses, bacteria and cancer cells through its nucleoside parent structure, and then the replication of RNA and DNA of these lesions can be blocked by virtue of the difference with the natural nucleoside structure to achieve the purpose of treatment.