Further explanation is that the newly discovered (deoxy) nucleotide sequence (not necessarily a gene, such as interfering RNA) can be patented as long as its function is clear. If this (deoxy) nucleotide sequence is prepared by a special preparation method, such as high yield, the method itself is also available. Of course, if a new function or better preparation method is found for a known (deoxy) nucleotide sequence, you can also apply for a patent for this new function or preparation method. It should be noted that whether you can apply for a patent depends mainly on whether you have "discovered" the "new effect" related to this (deoxy) nucleotide sequence, and has nothing to do with the similarity (homology) between this (deoxy) nucleotide sequence and the published sequence. For example, if only one base of a published gene is changed, and the expression efficiency is obviously improved, the changed gene can apply for a patent, although the overall sequence has not changed much; On the contrary, even if you change the base of a published sequence by more than 50%, all its functions have not changed, and you still can't apply for a patent.