1, use antibiotics as soon as possible;
2. Dosage and individualized medication should be based on local conditions and pharmacokinetics;
3. The choice of antibiotics should have good lung penetration;
De-escalation therapy, that is, first using broad-spectrum antibiotics to attack empirically, and then switching to relatively narrow-spectrum and targeted antibiotics in time according to the results of pathogenic examination and clinical response, can improve the prognosis of patients, reduce bacterial resistance, avoid adverse reactions or complications of broad-spectrum antibiotics treatment, and reduce costs. For infants who do not respond to ampicillin or penicillin, have HIV infection and exposure, and have severe or extremely severe pneumonia, ceftriaxone alone is recommended as second-line treatment (evidence quality: low; Recommended intensity: it depends). The choice of antibiotics depends on the patient's age, severity of illness and pathogenic microorganisms. The general course of treatment is 10d~ 14d when rales disappear.