For the sequence exactly the same as the reported sequence, it is not worth applying for a patent, because it does not meet the requirements of patent novelty (there is no same technology before the patent application date). Not exactly the same, which means it is novel.
On the basis of novelty, as long as the requirements of creativity are met, a patent can be obtained (the practicality of the three requirements of a patent is generally available). Creative judgment may require a person with certain patent knowledge to make a better judgment, but generally speaking, if it is inconsistent with the existing genes, it is somewhat creative.
It is recommended to entrust a special patent agency (generally called XXX Intellectual Property Agency Co., Ltd.) to apply for a patent for you (any one in the country can do it), because patent application requires higher professional skills. Only professionals can do professional things, otherwise, if you disclose your technology and get the patent right at the same time, it will not be worth the candle.