What are the radioprotective agents
What are the radioprotective agents? Health is the premise of personal happiness. It can be said that without health, there is nothing, which shows the importance of health to us, and the development of the health industry is constantly growing. The following shares what medicines are available for radiotherapy protective agents. What are the radioprotective agents? 1
Radiotherapy is radiotherapy, which is a local treatment method that uses ionizing radiation of radiation to cause damage to malignant tumors and benign lesions. Radiotherapy itself does not need to use drugs, but uses ionizing radiation to achieve therapeutic purposes. However, in order to improve the curative effect and reduce or treat the side effects, some drugs may be used to alleviate the side effects.
1. Drugs to improve the curative effect: In order to improve the curative effect, radiotherapy sensitizers, such as sodium glycididazole and irisquinone capsules, can be used to change the reactivity of tumor cells to radiation, increase the killing effect of ionizing radiation on tumor cells, and improve the control rate and cure rate of tumors. You can also use targeted drugs combined with radiotherapy, such as nimotuzumab and cetuximab, and you can also choose to use aminophosphine tincture as a radiotherapy protector, which can selectively protect normal tissues and cells;
2. Drugs to alleviate or treat side effects: In order to alleviate or treat side effects, dehydration drugs such as mannitol can be used to alleviate brain edema during brain radiotherapy. If the digestive tract mucosa breaks after radiotherapy, gastric ulcer and oral ulcer appear, mucosal protective agents, such as colloidal bismuth pectin capsules and bismuth potassium citrate capsules, can be used;
3. Others: radiotherapy patients can use immune enhancers to enhance their physique and promote the recovery of diseases, such as lentinan tablets and thymosin injection. If the patient's pain is obvious or there is a risk of infection, painkillers and anti-inflammatory drugs can also be used, such as acetaminophen tablets and amoxicillin clavulanate potassium capsules. What are the radioprotective agents? 2
Biafen cream < P > Biafen cream is mainly composed of triethylamine alcohol, which is rich in various active components such as cetyl palmitate. Pharmacological effects show that triethylamine alcohol can stimulate macrophages, induce macrophages to act on damaged parts, remove cell debris and inflammatory secretions, reduce the concentration of blood interleukin -6, and inhibit the inflammatory reaction of the body. As an oil-in-water cream, Biafen has deep hydration, which can block the dissociation of water molecules in skin cells by radiation.
Many studies have shown that Biafen can improve the radiation tolerance of skin in radiotherapy area, reduce the degree of skin lesions, and is beneficial to the recovery of skin lesions in the later stage.
rifuning ointment
the main component is aloe gel, the matrix is hard acid, lanolin and polyethylene glycol, and the preservatives are methyl paraben and propyl paraben.
Aloe contains a variety of essential amino acids and rich active enzymes, which is beneficial to skin metabolism, and also has good pharmacological effects such as bacteriostasis, anti-inflammation and wound healing. Aloe polysaccharide can promote the proliferation of epidermal cells.
A study of 6 patients with nasopharyngeal carcinoma who received radiotherapy showed that the patients who used this skin protectant had less skin damage.
Another study involving 6 patients with nasopharyngeal carcinoma also reached a similar conclusion. < P > Among them, 3 patients served as control group, and only received routine nursing. The other 3 patients were the experimental group, who were given rifuning on the basis of routine nursing. No grade 3-4 radiation skin injury occurred in the experimental group, and the number of cases of grade 1-2 radiation dermatitis was 28 cases and 2 cases respectively. In the control group, there were 1 patients, 15 patients and 5 patients with grade 1-3 radiation dermatitis respectively.
Beyoufen
The main structure of Beyoufen skin protectant is a gel composed of amino grape derivatives and glycerol. Polyamino grape has good moisture, which can replenish moisture to skin quickly, and also has strong antibacterial effect, which is beneficial to skin repair after radiotherapy.
Through the osmotic principle, the skin can be kept clean and moist, and at the same time, the local blood circulation can be increased, which effectively reduces the skin edema in the radiotherapy field; It can effectively relieve the pain and discomfort caused by local skin inflammation and dryness caused by radiation. Increase the tolerance of local skin to radiation.
The effects of this skin protectant on 4 patients with head and neck radiotherapy were studied and analyzed. There were 34 cases with grade 1 and 6 cases with grade 2 radiation dermatitis. No radiation dermatitis of grade 3 or above occurred.
3M liquid dressing
3M liquid dressing is a kind of polymeric solution, the main components of which are acrylate * * * polymer, hexamethyldisiloxane, polyethyl benzyl siloxane and isooctane. Its function is to quickly form a hidden colorless breathable membrane on the skin in the radiation field, which can effectively and safely protect local skin from adverse stimulation for 24-72 hours, so as to reduce the skin photosensitive reaction. Because of its strong antibacterial and bacteriostatic properties, 3m liquid dressing can effectively and safely protect local skin from adverse stimulation.
Similarly, 4 patients with head and neck radiotherapy were treated with this skin protectant, and the number of cases with grade 1 and 2 radiation dermatitis was 31 cases and 9 cases respectively. No radiation dermatitis of grade 3 or above occurred.
Another 4 patients with head and neck radiotherapy were treated with 3M liquid dressing and Beyoufen, and the protective effect seemed to be better. There were 4 cases of and 1 grade radiation dermatitis and 36 cases respectively. No radiation dermatitis of grade 2 or above occurred.
Furenmi
Furenmi is a kind of water-active colloid that can promote wound healing, and it mainly contains polyacrylic acid polymer, polyethylene glycol, arginine, branched fatty acids, methylparaben and methylparaben.
hydrocolloid can cover and protect the wound and create a suitable moist healing environment for the wound; Arginine can accelerate cell regeneration, thus reducing the possibility of scar formation; At the same time, hydrogel can promote the decomposition of necrotic tissue and damaged tissue.
Studies have shown that wound healing gel is superior to radiotherapy skin protectant in preventing acute radiation-induced skin injury. What are the radioprotective agents? 3
1. In the process of radiotherapy, we should choose appropriate drugs to effectively alleviate the disease to a certain extent. Alkylating agent is a commonly used chemotherapy drug, so it is best to choose some anticancer drugs during chemotherapy, and antimetabolites are also commonly used drugs during treatment.
2. Anti-tumor antibiotics are commonly used drugs, which can effectively prevent the spread of cancer cells in the process of chemotherapy, and anti-tumor plant components can effectively alleviate the symptoms. It also has a good effect on preventing some side effects after chemotherapy and avoiding the phenomenon of physical weakness.
3. Anti-tumor hormones are commonly used drugs in medicine, which can effectively prevent other complications. There are also many anti-tumor drugs and adjuvant drugs, which can effectively alleviate the symptoms of physical discomfort. When using drugs during chemotherapy, we must make reasonable adjustments according to the patient's condition.
Note:
If some people have malignant tumors, they can also be adjusted by using chemotherapy. In the process of chemotherapy, the choice of drugs is very important, and it can also be used to alleviate the disease and prevent the recurrence of the disease to some extent.