Ichthyosis is a rare genetic skin disease usually caused by a lack of keratin and lipids. The disease can be traced to a person's genes. Therefore, we can say that ichthyosis is caused congenitally.
Congenital means the disorder is present before a person is born. During embryonic development, genetic mutations in human cells can lead to ichthyosis. These mutations affect the formation and function of corneocytes, causing the stratum corneum to become thicker, harder, and unable to shed properly. This results in fish scale-like patches appearing on the surface of the skin.
Although ichthyosis is congenital, it does not necessarily manifest immediately after birth. Some patients may begin to experience symptoms in infancy or early childhood, while others may not develop noticeable signs until adulthood. This depends on the specific circumstances of each patient's genetic mutation and the impact of environmental factors on gene expression.
Although ichthyosis is congenital, acquired factors may also influence the development of the disease. People with ichthyosis often have dry skin that lacks moisture and oil. Factors such as dry climate, excessive cleansing, and prolonged exposure to water can worsen skin conditions. Infections, trauma, and some medications may also worsen the symptoms of ichthyosis.
Ichthyosis is congenital and caused by genetic mutations. Although acquired factors may have a certain influence on its development, the main reason is determined by genes. Understanding the mechanisms and influencing factors of this disease is important to effectively treat and manage the health of patients with ichthyosis.
Ichthyosis is a congenital hereditary skin disease caused by genetic mutations. Although acquired factors may influence its development and manifestations, such as the environment and medications, the basic cause is still genetically determined. Understanding this issue can help to better understand this rare and complex skin disease and provide patients with more effective treatment and management.