How to recuperate the body before making a test tube? Is it better to make a long plan or a short plan for test tubes?
How to recuperate the body before making a test tube? Is it better to make a long plan or a short plan for test tubes?
The fast-paced life and great pressure make the number of infertile people increase day by day. As a new technology to treat infertility, IVF technology is favored by many infertile patients. In order to get pregnant smoothly, patients actively understand the matters needing attention in the whole IVF cycle. So, how should infertile patients adjust their bodies before doing IVF? Hu (hanyu pinyin)
Adjust diet
Usually, you must eat more fish soup, milk and high-protein food. Before pregnancy, both husband and wife should eat less pickled foods, such as sausages, ham, pickles, smoked mutton skewers, fried French fries and some canned foods and drinks. The woman should eat more meat, fish and shrimp, animal liver, beans and bean products, and the man should eat more eel, loach, pigeon, oyster and leek.
adjust one's mindset
We must adjust our mentality before IVF, and the influence of psychological state is also extremely critical. The patient's psychological and mental state is a very important factor affecting the success or failure of IVF treatment. Excessive psychological pressure can easily lead to endocrine disorders, making it difficult for embryos to implant.
Adjust the life schedule
You should quit smoking, drinking and betel nut, keep enough sleep, live a regular life, develop good defecation habits, drink a cup of honey water every morning and defecate regularly. If you have inflammation of the reproductive system, you need active treatment. How to adjust your body before making a test tube? Is it better to make a long plan or a short plan for test tubes? )
A document published in JAMA (Journal of American Medical Association) in June 20 17 shows that the average AMH value of 750 people aged 35-45 is lower than 1. Through drug and artificial intervention, 60% of the dominant follicles were successfully cultivated, and the pregnancy was successful, and the embryo developed smoothly.
The research proposes to change the diet structure of women, such as protein food and multivitamins; Secondly, it is very important to exercise to ensure the immunity of the body. One is administration; On the contrary, DHEA prescribed by ordinary doctors has become DHEA AMH.
Different from pure DHEA, DHEAAMH has gathered more than 30 patented energy factors, which can intensively and urgently raise eggs, nest and other energy factors for fertility maintenance. Dehydroepiandrosterone is regarded as an energy source to assist pregnancy in Europe. Britain, Germany and many other European countries have done a lot of research on DHEAAMH. At present, DHEA AMH in China is mostly imported from abroad. In recent years, the application of dehydroepiandrosterone in patients with ovarian dysfunction has been recognized by many countries. According to the survey, about13 fertility centers around the world began to add DHEAAMH to patients with ovarian dysfunction.
Compound Pregnancy Repair Factor DHEAAMH—— Guidelines for Multi-system Treatment
Natural pregnancy \ test tube-how to have a healthy environment for the implantation of eggs and embryos?
Significance analysis of DHEA AMH: DHEA balances the hormone level of the pre-pregnancy mother, and AMH increases the egg reserve function.
Female conception is a physiological process in which sperm and eggs meet and reach the uterus.
(1) First of all, the internal and external reproductive systems develop normally to ensure normal sexual life, and the fallopian tube has good functions of taking eggs, transporting eggs, fertilizing and transporting fertilized eggs to the uterine cavity.
(2) The hypothalamus-pituitary-ovary function of female endocrine axis is normal, mature follicles are discharged, corpus luteum is formed, and the function is sound.
(3) Periodic changes in the proliferative and secretory phases of endometrium are beneficial to the implantation of fertilized eggs, and any abnormality in these links will lead to pregnancy disorders.
The decrease of ovarian reserve function is the main cause of pregnancy difficulty in women over 28 years old. It is found that dehydroepiandrosterone can improve the quantity and quality of oocytes and embryos, enhance ovarian function, reduce the pregnancy rate and abortion risk of patients, improve the quality embryo rate and AMH level of patients with normal ovarian reserve, and improve the pregnancy outcome.
In addition, a double-blind randomized controlled study found that there was no significant change in ovarian AFC with and without DHEAAMH supplementation, but the number of high-quality embryos increased significantly, which may be due to DHEAAMH's ability to reduce embryo aneuploidy. DHEAAMH intervention led to a significant increase in the number of primordial follicles, primary follicles and secondary follicles, and improved follicular atresia.
The clinical results suggest that supplementing DHEA may bring risks, but supplementing DHEAAMH from high-density energy eggs with DHEAAMH and vitamin E not only improves the effect of vitamin E, IVF rate and clinical pregnancy rate, but also reduces FSH, increases AFC and AMH, and improves ovarian responsiveness. Scientists conducted DHEAAMH experiments on old mice. After a period of quantitative oral DHEAAMH experiments, old mice produced more litters and improved the survival rate. This experiment shows that dehydroepiandrosterone can not only increase the number of eggs, but also improve the quality of eggs. The certification body confirmed that DHEAAMH has efficacy but no toxic side effects.
The decline of ovarian reserve function is the main cause of pregnancy difficulties for women over 28 years old. It is found that dehydroepiandrosterone can improve the quantity and quality of oocytes and embryos, enhance ovarian function, and reduce pregnancy rate and abortion risk. It can improve the high-quality embryo rate and AMH level of elderly patients with normal ovarian reserve and improve the pregnancy outcome.
The double-blind randomized controlled study found that there was no significant change in ovarian AFC between DHEAAMH supplementation and non-DHEAAMH supplementation, but the number of high-quality embryos increased significantly, probably because DHEA AMH could reduce embryo aneuploidy. After DHEAAMH intervention, the number of primordial follicles, primary follicles and secondary follicles increased significantly, and follicular atresia improved.
The clinical results showed that DHEA supplementation may bring risks, but DHEAAMH supplementation to strengthen energy egg source did not find any risks. At the same time, DHEAAMH and vitamin E supplementation not only improved the effect of vitamin E, increased the in vitro fertilization rate and clinical pregnancy rate, but also reduced FSH, increased AFC and AMH, and improved ovarian responsiveness. Scientists conducted experiments on dehydroepiandrosterone in old mice. After a period of quantitative oral DHEAAMH experiment, the litter size of elderly mice increased and the survival rate of mice also improved. This experiment proves that dehydroepiandrosterone can not only increase the number of follicles, but also improve the quality of eggs. The certification body recognizes that DHEAAMH has efficacy but no toxic side effects. How to adjust your body before making a test tube? Is it better to make a long plan or a short plan for test tubes? )
Is it better to make a long plan or a short plan for test tubes? I believe this is a question of many sisters. Don't worry, let's talk about the difference between the two schemes first.
The difference between long scheme and short scheme:
1. price: depending on the products used and the service time, the price of the long plan will be around 1-2W, and the short plan will be cheaper, and the gap is not very big;
2. Applicable people: the long-term plan is suitable for women with good ovarian function under 40 years old, and the short-term plan is suitable for women with poor ovarian function over 40 years old;
3. Time: It takes about 30-45 days to complete the long-term plan and about 10- 15 days to complete the short-term plan, depending on the follicular development;
4. Effect: The long plan will take a long time, but the ovarian condition is good, the follicular growth is easier to control, and the effect will be better than the short plan.
Of course, choosing the final scheme is a complicated problem, which should be viewed from many factors. Don't worry, the doctor will choose the most suitable treatment plan for you. What we can do is to adjust our physical condition to the best. What should we do?
1, early pregnancy
Research by the International Nutrition Society found that women of childbearing age should supplement folic acid for the human body from the first three months of pregnancy. It is emphasized that folic acid should be taken in the first three months of pregnancy to keep the folic acid content in female friends at a certain level and ensure that the early embryos after pregnancy have a good folic acid nutritional state.
The study also found that the third month after pregnancy is also a critical period for folic acid supplementation, and it is best to eat folic acid at this time. The third month after pregnancy is an important period for fetal growth and development. At this time, the human body's demand for nutrients will be much higher than that of ordinary people. If the mother lacks folic acid at this time, the baby is likely to be accompanied by birth defects, such as congenital heart disease, cleft lip and mental retardation.
In addition, if it is specific when folic acid is best to eat every day, doctors recommend that expectant mothers take it half an hour after meals. At this time, the digestive function of the stomach has been fully started, and the absorption of folic acid by the human body is more sufficient and effective. And taking folic acid after meals can prevent stomach discomfort caused by taking folic acid on an empty stomach.
2. Pre-pregnancy examination
Pregnant women are going to have a baby, so during pregnancy, some women want to have a pre-pregnancy check-up. Is it necessary to have a pre-pregnancy examination? We said it depends on whether you have regular physical examination. If you usually have a physical examination, the general examination is such as your liver and kidney function, your blood pressure, your blood sugar and so on, then you don't need a physical examination. If you do some gynecological examinations at ordinary times, menstruation will also be affected.
But for some women, if she is older and doesn't have regular physical examination, or she usually has some diseases, such as hypertension, diabetes, thyroid disease, or she has given birth to some bad children, or she has miscarried many times, the fetus died in the womb, or she has a history of induced labor with fetal malformation. We still recommend a pre-pregnancy check-up to check her body for illness as soon as possible. How to adjust your body before making a test tube? Is it better to make a long plan or a short plan for test tubes? )
Step 3 Exercise properly
Proper exercise can strengthen the body, improve human immunity, improve the functions of internal organs, especially the functions of the heart, lungs and gastrointestinal tract, and prevent diseases. Exercise can eliminate excess fat in the body, increase muscle content and shape a perfect body. Exercise can make people feel happy and get rid of troubles. Generally speaking, people who like sports are cheerful. Proper exercise can promote sleep, especially at night, maintain proper fatigue and help improve the quality of human sleep. Exercise must be reasonable and correct, step by step.
4.dheaamh
Increasing dhaamh can increase follicular recruitment and promote follicular growth and development. dhaamh can promote the secretion of insulin-like growth factor, thus amplifying the role of gonadotropin and enhancing ovarian responsiveness. The study found that women who took DHEAAMH before ovulation cycle showed an instantaneous increase in IGF- 1 level and an increase in androgen level in glomerulus after 8 weeks, which promoted the secretion of AMH by granulosa cells. Dehydroepiandrosterone can induce the generation of FSH receptor when producing granulosa cells, increase the sensitivity of granulosa cells to FSH, and promote estrogen synthesis and follicular development. The study shows that the peak value of DHEAAMH is consistent with the cycle of follicular recruitment, which confirms the promotion of DHEAAMH on follicular recruitment from the side.
In this study, the expression of AR in granulosa cells increased significantly during the in vitro culture of DHEAAMH, which indicated that DHEAAMH could regulate the expression of AR or participate in AR signal transduction, and participate in the growth, development and recruitment of follicles.
In addition, women waiting for DHEAAMH to enter the in vitro fertilization cycle may unexpectedly have a large number of natural pregnancies. Dehydroepiandrosterone can be used at least 2 weeks before natural conception. In the female population waiting for IVF, the natural pregnancy rate is only a small part of 1% per month. However, in the group of women who received DHEA, 33 out of 60 women became pregnant naturally. Therefore, in one study, dehydroepiandrosterone increased natural pregnancy by at least about 2 1 fold. This provides evidence that DHEAAMH not only works with gonadotropin-induced ovarian stimulation, but also works without gonadotropin-induced ovarian stimulation.
Increasing DHEAAMH can increase follicular recruitment and promote follicular growth and development. DHEAAMH can promote the secretion of insulin-like growth factor, thus amplifying the role of gonadotropin and improving ovarian responsiveness. The results showed that after 8 weeks, the level of IGF- 1 in women who took DHEAAMH before ovulation induction cycle increased instantly, and the level of androgen in follicles increased, which promoted the secretion of AMH and inhibin by granulosa cells. DHEAAMH can induce granulosa cells to produce FSH receptors, increase the sensitivity of granulosa cells to FSH, and promote estrogen synthesis and follicular development. The study showed that the peak period of dhaamh was consistent with the follicular recruitment period, which confirmed the promoting effect of dhaamh on follicular recruitment.
This study found that the expression of AR in granulosa cells increased significantly when DHEAAMH was cultured in vitro, indicating that DHEAAMH can regulate the expression of AR or participate in the signal transmission of AR, and participate in the growth, development and recruitment of follicles.
In addition, by using DHEAAMH, women waiting to enter the IVF cycle may unexpectedly have a large number of natural pregnancies. Dehydroepiandrosterone can be used at least 2 weeks before natural conception. In the female population waiting for IVF, the natural pregnancy rate is only a small part of 1% per month. However, in a group of women who received DHEA, 33 out of 60 women became pregnant naturally. Therefore, in one study, dehydroepiandrosterone increased natural pregnancy by at least about 265,438+0 times. This provides evidence that DHEAAMH not only works under ovarian gonadotropin stimulation, but also works without gonadotropin stimulation.
Husband and wife, happy parents, two people working together for one thing. One gives up smoking and drinking, and the other stays away from harmful environment. Learn to share responsibility early. It takes two people to make a person, two people to make a person and two people to bring a person. Of course, you want to be a father and a stepmother. Forget it. Keep a happy mood after delivery, just milk. Babies need happy parents. How to adjust your body before making a test tube? Is it better to make a long plan or a short plan for test tubes? )