Generic name: rapatinib mesylate tablets, abbreviated as rapatinib.
English names: Tykerb, Tyverb, lapatinib
Specification: 250mg
Manufacturer: GlaxoSmithKline (GSK)
Combined with capecitabine for the treatment of advanced or metastatic breast cancer with ErbB-2 overexpression, which was previously treated with anthracyclines, paclitaxel and trastuzumab (Herceptin).
Herceptin
Tratuzumab for injection
English name: Herceptin, trastuzumab
Specification: 440mg/ piece
Manufacturer: Roche Company
Herceptin is suitable for the treatment of metastatic breast cancer with overexpression of HER2.
As a monotherapy for metastatic breast cancer that has received 1 or more chemotherapy regimens;
Combined with taxanes in the treatment of metastatic breast cancer, no chemotherapy is needed.
The difference between the two is that:
① Theresa/rapatinib is an oral drug.
Herceptin was injected intravenously.
③ Herceptin is only for HER2.
④ Rapatinib is a multi-target drug against HER2 and HER 1, and it is a small molecule compound, which may pass through the blood-brain barrier more easily.
Rapatinib has been listed in China, 20 13, which is sold by Ito Pharmaceutical Co., Ltd., and should be sold in all major hospitals.