Main research directions: genetic engineering drugs; research on medicinal functional genes derived from plants; mining and utilization of targets and construction of screening platforms;
Main scientific research projects undertaken in the past five years: 1. National Natural Science Foundation of China Youth Fund Project, Research on the Effect and Mechanism of Transferrin Carrier on Improving the Performance of vMIP-Ⅱ Drugs, No.: 30700704, 2008.1-2010.12, Project Leader 2. Science and Technology Innovation Project of Guangdong Provincial Department of Education, SOD Reform The role of constructs and related miRNAs in inhibiting tumor development and metastasis, No.: 34312017, 2012.1-2013.12, Project Leader 3. Guangdong Provincial Natural Science Foundation, using Pichia pastoris to express the long-acting AIDS entry inhibitor vMIP-II, No. : 06300563, 2006.10-2008.10, project leader 4. Open research project of the Key Laboratory of Regenerative Biology, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, the role and regulation of PTD-antioxidant enzymes and related miRNAs in the reprogramming process of ips cells Research number: KLRB201105 2012.01-2013.12, Project leader 5. Guangdong Provincial Medical Science and Technology Research Fund, Biological functions of human manganese superoxide dismutase gene splicing isoforms, No.: B2008095, 2008.6-2011.6, Project leader 6 . Guangdong Provincial Medical Science and Technology Research Fund, Research on the Effect of vMIP and its Polypeptides on Cell Surface Chemokine Receptors, No.: A2006356, 2006.6-2009.6, Representative works or patents of the project leader in the past five years: 1. Wang Feng , Li Xiuying, Mo Xuemei, Guang Zhang, Sun Hanxiao. A biologically active vMIP-II-IgG3-TfN fusion protein, secreted from methylotrophic yeast Pichia pastoris. Protein Expression and Purification, 2012, accepted. 2. Wang Feng, Shao Mei, Yang Wenjie, Huang Luyuan. High-level Soluble Expression of Recombinant Human Manganese Superoxide Dismutase in Escherichia coli, and its Effects on Proliferation of the Leukemia Cell. Protein Expression and Purification, 2011, 77(1), 46-52 3. Wang Feng , Wang Hongbin, Liu Bing, Wang Jinfa. Cloning and Characterization of a Novel Splicing Isoform of Iron-Superoxide Dismutase Gene in Rice. Plant cell reports. 2006, 24(12): 734-742. 4. Wang Feng, Sun Hanxiao, Li Xiuying, Zhang Guang, Mo Xuemei. Expression and purification of vMIP-II-TfN fusion protein in Pichia pastoris. Chinese Journal of Biotechnology, 2011, 31(10): 23-28 5. Wang Feng, Huang Luyuan. Mouse manganese Expression and purification of superoxide dismutase in Escherichia coli. Journal of South China Agricultural University
.2010, 31(3): 85-89 6. Wang Feng, Huang Luyuan. Expression analysis of splice isoforms of human manganese superoxide dismutase gene. Biotechnology Bulletin, 2010, 3, 164-167 7. Wang Feng, Yang Wenjie, Cheng Zifeng, Huang Luyuan. Amplification and expression study of human manganese superoxide dismutase. Pharmaceutical Biotechnology, 2009, 16(4): 302-305 8. Wang Feng, Wang Hongbin, Wang Jinfa. Rice cytoplasmic Cu/Zn-SOD gene Sequence and expression analysis. Journal of Tropical and Subtropical Botany, 2007, 15(2): 101-106 9. Wang Feng, Huang Luyuan. Sequence characteristics analysis of human serum albumin gene. Shandong Medicine. 2006, 46(35): 3-4 10. Wang Feng, Sun Hanxiao, Mo Xuemei, Li Xiuying, Zhang Guang. Construction and application value of universal transferrin fusion expression vector. Biotechnology Bulletin, 2010, 8, 98-101 11. Wang Feng, Sun Hanxiao. Research progress on chemokines and their receptors and AIDS. Chinese Journal of New Drugs. 2007, 2007, 16(16): 1243-1246 12. Wang Feng, Wang Jinfa. Construction and preliminary analysis of cDNA libraries of rice young leaves and spikes. Journal of Sun Yat-sen University, 2005, 44(2): 74-77 13. Wang Feng, Huang Luyuan. Development of binary Ti carriers. Journal of Northwest Botany. 2006, 26(11): 2397-2401 14. Wang Feng, Lu Yongen, Li Hanxia. Several Study on kanamycin resistance of cabbage vegetables. Wuhan Botany Research, 2006, 24(4): 377-380 15. Wang Feng, Huang Luyuan, Wang Hongbin, Liu Bing, Wang Jinfa. One-step RT-PCR cloning of rice mitochondria Analysis of phosphate transporter genes and their sequence characteristics. Journal of Tropical and Subtropical Botany, 2005, 13(4): 303-309 16. Hua Xing, Wang Feng, Mo Xuemei, Li Xiuying, Zhang Guang, Xu Hua, Sun Hanxiao. vMIP-Ⅱ Study on the internalization and modulation of cell surface chemokine receptor CXCR4. Modern Immunology, 2006, 26(2):17-20 17. Guo Qinli, Wang Feng, Sha Wenqiong, Mo Xuemei, Li Xiuying, Xu Hua, Zhang Guang, Sun Hanxiao. Effect of vMIP-Ⅱ on TCRVβ gene expression in SIV-infected cynomolgus monkeys. Journal of Immunology, 2006, 22(6): 604-607 18. Ye Shidun, Mo Xuemei, Zhang Guang, Li Xiuying , Wang Feng, Sun Hanxiao. Analysis of binding active sites of vMIP-II receptors. Chinese Journal of Modern Medicine. 2006, 16(23): 3546-3548
Main social part-time jobs:
Member of Chinese Pharmacological Society