The definition of the first toothbrush is very broad, but the first machine assembly line was manufactured by DuPont. The previous invention was not made by one person. There were various types of similar toothbrushes around the world before 1700. The prototype of the early toothbrush appeared, so if there is a demand, there will be an invention. Many inventions are not the work of one person, but are accumulated in many aspects over a long period of time. In fact, similar prototypes of inventions already existed before many inventions appeared. Brushing teeth only appeared when humans realized the importance of oral hygiene. Although it only appeared in a few high-class and pampered people at first, and the methods of brushing teeth were different, and the brushing utensils were also very different, but in the end it was simple and practical. It became popular and was adopted by business figures with sharp business acumen. They then let specific technical personnel develop and manufacture it and then applied for patents and brands.