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A, the essence of programmable cells is that they can selectively express genes, indicating that programmable cells can also differentiate, so their characteristics can be comparable to those of stem cells, and A is correct;

B, the process from mature leukocytes to programmable cells is similar to dedifferentiation in plant tissue culture, that is, from highly differentiated cells to redifferentiated cells, B is correct;

C, reprogrammed cells can further differentiate into cells with different functions, thus making it possible to radically cure some diseases. C is correct;

D, the essence of "programming" is to use specific technology to selectively express genes, rather than transforming genetic material, D error.

Therefore, choose: d.