International inscriptions classify 80% concentration of nuciferine as high-purity nuciferine, and the extraction process of high-purity nuciferine is complicated, so most domestic nuciferine preparation enterprises cannot extract it independently.
Most high-purity lotus leaf alkali demand enterprises can only rely on imports. Japanese enterprises generally adopt patented microwave pulverization technology after the first extraction process of nuciferine, but the cost is extremely high.
Lee-ma Research Center is using separation and extraction method to extract nuciferine with purity over 98%, and has made a breakthrough. At the same time, the LUX membrane separation technology patented by the United States is the most recognized extraction process of nuciferine in the world at present, which can effectively separate the impurities and water (that is, ultra-fine molecular nuciferine) from the nuciferine extracted in the first step, and the physiological purification is over 90%.