Overview of R&D of Qingdao Guofeng Pharmaceutical Co., Ltd.

The R&D Department of Qingdao Guofeng Pharmaceutical Co., Ltd. was integrated by the Shandong Provincial Institute of Marine Pharmaceutical Sciences and the Research Institute of Qingdao Guofeng Pharmaceutical Co., Ltd., and was recognized as a "provincial-level research institute" in 1997. Technology Development Center".

The R&D Department consists of the Scientific Research Management Section, the Technology Section, and four key laboratories - Traditional Chinese Medicine Research Laboratory, Natural Medicine Research Laboratory, Chemical Drug Research Laboratory, and Drug Analysis Laboratory. Among them, the Traditional Chinese Medicine Natural Medicine Research Laboratory mainly focuses on the modernization of traditional Chinese medicine, research on modern drug preparations and health food research, and is the main technical support for the company's traditional Chinese medicine varieties; the Natural Medicine Research Laboratory is mainly engaged in the research and development of marine active substances; chemical drugs The research laboratory is mainly engaged in the research and development of biosynthetic drugs; the drug analysis laboratory is mainly engaged in drug analysis and quality standard research. The Technology Section is mainly responsible for the research of large-scale production process parameters, optimization and improvement of process routes, solving problems existing in the process, formulating and publishing production process regulations, etc. The R&D Department also hosts the national academic journal "Chinese Marine Medicines".

The R&D Department has gathered a group of top-notch young and middle-aged scientific and technological talents composed of doctors and masters, forming a scientific research team with a good foundation and strong strength.

In addition to various conventional experimental instruments, the R&D department currently owns the American Beckman Biosys2000 development protein purification workstation, Waters 600 liquid chromatograph, Waters 515 liquid chromatograph, and Agilent1200 Liquid chromatograph, Agilent 1260 liquid chromatograph, Agilent 6890 gas chromatograph, Karma Scanner-3 dual-wavelength thin layer scanner, Shimadzu UV-2550 ultraviolet spectrophotometer, Nicolet avatar 370 infrared spectrometer, Pharma-test Dissolution apparatus, BINDER constant temperature and humidity chamber, millipore ultrapure water machine, J2-MC high-speed refrigerated centrifuge, low-temperature freeze drying oven MFD-35 type, Beijing Rayleigh atomic fluorescence instrument AF-610A type, BUCH rotary evaporator, American Snowflake Ice making machines and other domestically leading experimental testing instruments. The pilot base is equipped with domestic leading countercurrent dynamic extraction, multi-effect evaporation units, resin separation columns, spray dryers, spray drying one-step granulators, dry granulators and other equipment.

The main research direction in recent years is the research and development of traditional Chinese medicine, natural medicine and marine medicine, while also expanding into the research and development fields of chemical drugs and health food. The use positioning of new products mainly focuses on cardiovascular and cerebrovascular diseases, respiratory diseases and digestive system diseases. Through continuous exploration, we have gradually established a research and development model that combines independent development with industry, academia, and research. So far, it has established cooperative relationships with more than 10 well-known domestic universities, scientific research institutes and private institutions, and has had successful cooperation with more than 10 domestic leading clinical pharmacology bases.

In recent years, the R&D Department has obtained 14 new drugs approved by the state, 4 health food products, 9 national invention patents, and 10 projects currently under research.