Patented drugs for nephropathy

Proteinuria is a barometer of renal function. If it is maintained at a low level for a long time, the renal function will be more stable and the risk of renal failure will be reduced. However, proteinuria is a naughty indicator, which will rise repeatedly for some casual reasons, such as eating too much high-protein food in a short time, sudden cold infection and so on. Therefore, it is necessary for kidney friends to make more efforts to control proteinuria. In addition to avoiding these inducing factors and reducing the influence of proteinuria on renal function, the most important thing is to adhere to drug treatment, and to protect glomerulus from damage by inhibiting the immune inflammatory reaction of kidney, so as to fundamentally inhibit protein leakage. The combination of hormone and immunosuppressant has obvious advantages in eliminating inflammation, but it has no obvious effect on protecting glomerulus and stabilizing renal function. This is the reason why some patients will relapse even though they take hormones on time. Is there any medicine that can kill two birds with one stone in reducing proteinuria and delaying renal function? These non-therapeutic drugs for kidney disease may come in handy! ——ACEI and ARB drugs, the "old friends" who protect kidney, are not "professional" drugs for treating kidney diseases, but they play an important role in lowering protein level and delaying renal function, and have become commonly used drugs for lowering blood pressure and protein in the treatment of kidney diseases. Powdered drugs are angiotensin converting enzyme inhibitors, and sartans are angiotensin receptor blockers. The mechanism of action of these two drugs is the same, and ultimately they all inhibit vascular tension and lower blood pressure by inhibiting the renin-angiotensin-aldosterone system (RASS). With the decline of renal function, patients with nephropathy will have different degrees of blood pressure increase. Controlling blood pressure itself is beneficial to improve renal ischemia and hypoxia, stabilize renal function and reduce protein leakage. In addition, patients with chronic kidney disease often have intraglomerular hypertension. Puluoli or sartan can reduce the pressure in glomerulus and the burden of renal filtration, thus reducing urinary protein, protecting renal function and reducing uremia. Many kidney friends with hypertension and proteinuria must be familiar with these two kinds of drugs. Need to remind them that these two drugs will lead to an increase in creatinine. Don't worry if it doesn't exceed 20%, but remember to monitor the creatinine value. Diuretic swelling-spironolactone seems to be less famous than the above two kinds of drugs. Spironolactone has diuretic, detumescence and potassium excretion effects on other diuretics. Patients with proteinuria, due to poor glomerular filtration, lead to water and sodium retention, coupled with protein leakage, often accompanied by edema of both lower limbs. Spironolactone can effectively eliminate renal edema, help maintain the balance of water and electrolyte in the body, thus stabilize the glomerular filtration function and help reduce the level of proteinuria. Compared with Shatanlei and paracetamol, it has fewer side effects and higher safety in reducing protein. Treating stomach and kidney-I have heard that sodium bicarbonate is very important for treating stomach diseases and kidney diseases. It is not common to treat stomach diseases and kidney diseases at the same time. Sodium bicarbonate is one of them. Feel the name of this medicine is particularly familiar? Actually, it has a common name-baking soda. Sodium bicarbonate is a commonly used medicine for treating stomach diseases, mainly used for treating stomachache, heartburn, acid reflux and heartburn. In the treatment of nephropathy, it is mainly to improve the acid-base imbalance. After kidney damage, the function of regulating water, electrolyte and acid-base balance decreases, and patients with acid-base imbalance are prone to metabolic acidosis. Taking sodium bicarbonate is beneficial to improve this situation, neutralize the acid in the body and reduce the burden of kidney metabolism. It can protect renal function and help to control the stability of proteinuria. It can be seen that impaired renal function will lead to systemic lesions, and the quality of each symptom will eventually affect renal function, and then affect proteinuria. Therefore, the treatment of nephropathy should not only break through each symptom one by one, but also maintain the overall stability of renal function from a macro perspective, which is more helpful to greatly reduce the risk of uremia. (Note: See the watermark for the image source of the article. 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