Western medicine treatment
1, decongestant
It is concluded from clinical practice that most patients with allergic rhinitis are accompanied by nasal congestion, and improving this situation is also the key to treatment. The decongestant mainly acts on the patient's nose. By binding with adrenergic receptors on the vascular wall of nasal mucosa, nasal mucosal swelling is gradually relieved, and symptoms of nasal congestion and congestion are relieved. The general course of treatment is controlled within 7 days. Ephedrine, oxymetazoline and other commonly used drugs. However, drug treatment can slow down the symptoms, and at the same time, there will be symptoms such as nasal mucosa dryness, nose pain and tachycardia. Therefore, we must be careful when using decongestants, especially in patients with hypertension, heart disease and diabetes.
2. Mast cell stabilizer
Mast cell stabilizer in the treatment of allergic rhinitis, mainly by blocking the activation of phospholipase A on the surface of mast cells to achieve the effect of relieving patients' symptoms. Its representative drug is sodium cromoglycate. Sodium cromoglycate is an antiallergic drug, which can stabilize mast cell membrane and inhibit cell membrane division. After the drug enters the human body, it can take effect quickly and relieve symptoms such as stuffy nose, sneezing and itchy nose. Some patients have a burning sensation in the nose, but it does not affect the therapeutic effect.
3. Corticosteroids
Commonly used drugs in clinic include budesonide, triamcinolone acetonide and clomiphene citrate. Drugs can reduce the permeability of endothelial cells and epithelial cells and relieve nasal discomfort. However, clinical studies have found that such drugs may cause nasal burns, increased sneezing times and nosebleeds in patients (especially children). Therefore, we must pay attention to medication.
4, antihistamines
At present, fexofenadine, levocetirizine and other three generations of antihistamines have been widely used in clinic. These drugs are suitable for patients with mild persistent allergic rhinitis and mild intermittent allergic rhinitis. After the drug enters the human body, it takes effect quickly and brings relatively few adverse reactions to patients.
immunotherapy
It is understood that probiotic antiallergic therapy is a method based on immunology "IgE allergy mediation theory". This therapy mainly consists of patented anti-allergic probiotics (lactobacillus paracasei, Lactobacillus Roy, Lactobacillus acidophilus, etc. Immunologists have found that there are three main pathogenic factors of rhinitis: genetic factors, nasal mucosa susceptibility and antigenic substances. These three reasons are either the high content of lgE antibody or the external stimulation (commonly known as allergy) which leads to the increase of lgE antibody and the onset of rhinitis. Allergic rhinitis induced by external stimuli is particularly common. Xinminkang anti-allergic probiotics can achieve therapeutic effect by reducing and regulating the content of lgE antibody in serum. Anti-allergic probiotic strains bind to receptors on intestinal wall dendritic cells, activate intracellular transfer proteins to move to the nucleus and release a large number of cytokines, which is a link of innate immunity. Therefore, diabetic substances such as peptidoglycan, lipopolysaccharide and polysaccharide on its cell wall can activate the development of T cells through innate immune system. The World Health Organization (WHO) pointed out in its guidance on the treatment of allergic diseases: "Probiotic therapy is the safest and most effective method to completely cure allergic constitution."