Substitution position of sodium sulfobutyl betacyclodextrin

1-1 substitution. Sodium sulfobutyl beta-cyclodextrin is a polyanionic compound, and its substitution pattern is random, resulting in uneven mixture in substitution position (1-1 substitution) and degree of substitution (n). The result of this characteristic is that sodium sulfobutyl beta-cyclodextrin with the same molecular formula is far from the final effect and toxicity due to different production processes and different manufacturers.