List of this article: 1, efficacy and function of leeches 2. What are the efficacy of hirudin skin care? 3. What is natural hirudin? What's the role? Someone once told me about hirudin, but I didn't care. What exactly is hirudin? What's the effect? 5. What is the function of hirudin? Efficacy and function of leeches: efficacy and function of leeches.
Leech, also known as leech, is a blood-sucking annelids.
It is common to meet leeches in the wild.
Leeches are prone to infection after biting and sucking blood. Learn to protect yourself and calmly deal with attacks.
The following is the knowledge I brought to you about the efficacy and function of leeches. Welcome to reading.
Efficacy and function of leech
1, hemagglutination.
Hirudin can prevent blood coagulation, so it has antithrombotic effect.
2. Thrombolytic effect.
Hirudin can inhibit platelet aggregation and dissolve thrombus caused by thrombin.
Hirudin is a methanol extract, which can activate the chemical fiber dissolution system in vitro and in vivo. The salivary gland secretion of leech has strong antithrombotic effect after intravenous injection in rats.
3. Platelet effect in Hangzhou.
Hirudin can inhibit the combination of thrombin and platelets, promote the dissociation of thrombin and platelets, and inhibit the release of platelets stimulated by thrombin and the reaction induced by thrombin.
4. Influence on hemorheology.
Feeding leech extract 0.45g/kg to animals can reduce blood viscosity and shorten erythrocyte electrophoresis time.
Leech decoction can also reduce the whole blood specific viscosity, plasma specific viscosity, hematocrit and fibrinogen content in rats with abnormal hemorheology.
5. Hypolipidemic effect.
Leech powder (65438 0g/animal) gaves the stomach to hyperlipidemic rabbits every day. Both preventive and therapeutic drugs can reduce the contents of cholesterol and triglyceride in blood, and at the same time, the lesions of aorta and coronary artery are lighter than those in the control group, and the plaques are obviously subsided, which is characterized by collagen fiber proliferation and cholesterol crystallization reduction.
6. Influence on cardiovascular function.
Intraperitoneal injection of hirudin (30g/kg) can obviously increase the ability of myocardial uptake of 86Rb in mice, indicating that it can increase myocardial nutrient blood flow.
7. Termination of pregnancy.
Leech wide body can terminate the early, middle and late pregnancy in mice.
The leech decoction (2.5 ~ 3 g/kg) was injected subcutaneously twice on the first 1, sixth 10 day of pregnancy, which had a very significant effect on terminating pregnancy in mice.
8. Influence on experimental cerebral hematoma and subcutaneous hematoma.
Leech extract can promote the absorption of experimental cerebral hematoma in rabbits.
Experiments show that leech can promote the absorption of cerebral hematoma and subcutaneous hematoma, reduce peripheral inflammatory reaction and edema, relieve the increase of intracranial pressure, improve local blood circulation, protect brain tissue from necrosis and promote the recovery of nerve function.
9. Effect on experimental renal injury.
30% leech solution 15 ml/kg, given twice, has obvious preventive and therapeutic effects on early acute tubular necrosis caused by intramuscular injection of glycerol in rats, and the increase of blood urea nitrogen and serum creatinine is significantly lower than that in the control group.
The morphological changes of renal tissue were obviously improved.
Its mechanism may be related to improving hemorheology and hypercoagulability, thus improving renal blood circulation.
10, other functions.
Leech can also inhibit decidual tumors.
Low concentration leech extract has obvious contractive effect on rabbit uterus in vitro.
Hirudin can also inhibit the proliferation of fibroblasts induced by thrombin and the stimulation of endothelial cells by thrombin.
Medicinal value of leech
Breaking blood and dredging channels, removing blood stasis and eliminating symptoms.
It can be used for amenorrhea due to blood stasis, addiction, apoplexy, hemiplegia, and traumatic injury.
1. Women with unfavorable menstrual flow also treat men with bladder fullness and blood stasis: 30 leeches (boiled), 30 tabanus (boiled with wings and feet removed), 20 peach kernels (peeled and pointed) and three or two rhubarb (soaked in wine).
Take five liters of water, boil three liters, and raise the temperature except me.
("synopsis of the golden chamber" arrives at Dangtang)
2. The woman has blood stasis in her belly, and the moon water is unfavorable, or it breaks or comes, and her heart is full of anxiety: three peaches (soaked in soup, peeled and pointed by Shuang Ren, stir-fried with bran), forty tabanus (slightly fried with wings and feet removed), forty leeches (slightly fried with yellow), and two Huang San from Sichuan University (slightly fried with files).
The medicine is pounded into powder, and the honey is pounded into hundreds of pestles, and the pills are as big as buttonwood.
Take fifteen pills with hot wine.
("Sheng Hui Fang" Ren Tao Pill)
3, irregular menstruation, or postpartum lochia, umbilical pain: Rehmannia glutinosa 42, fifty scarabs (fried in Toma Evelle), leeches (glutinous rice, stir-fried glutinous rice), peach kernels (peeled tips).
The top is the bottom, honey pills, and tung fruit is big.
Take five or seven capsules each time, hollow warm wine.
(Dihuang Tongjing Pill, a secret recipe for women)
4, blood leakage is not limited: leeches are screened and treated, and wine is given a sum of money. The next day, the evil blood disappeared and healed.
(Qian Jinfang)
Broken: leeches, baked on new tiles, fine powder, hot wine to adjust the money, eat, pain can, more clothes, pain stops.
Then seal the bone-breaking medicine and fix it with something.
(Experience)
6, golden sore, injury and falling from a height, wood and stone bruises, internal injuries and blood stasis, chest pain, defecation, and anger: half a piece of red leech (fried with lime until brown), two pieces of rhubarb, and two pieces of black morning glory.
Every time you take San Qian, you should adjust it with hot wine. For example, after walking four or five miles, you should adjust it with hot wine and use two yuan to urge it. You must turn down the evil blood in the viscera and make it into pieces or blocks, and it will be fine as soon as the evil blood is consumed.
("Fang Jisheng" kills life)
Side effects of leeches
Physical deficiency and blood deficiency, no blood stasis, pregnant women should not take it.
1, Hua Yu Ben Cao: afraid of lime.
2, "Herbal Yi Yan": afraid of salt.
3, "Pinhui essentials": pregnant can not take.
Records in leech medical books
1, "Compendium of Materia Medica": Blood leaks, and the wine is fried to the end.
2, "Ben Jing": expelling evil blood and blood stasis, harvesting the moon, bleeding accumulation, childless, benefiting the waterway.
3, "medicinal nature": cure women's monthly closure, want to become blood work.
What are the effects of hirudin skin care? Hirudin, as one of the three major pigments in the world, has great value.
In recent years, hirudin has been widely used in skin care.
Hirudin has four functions in skin care.
1. has a small molecule and strong autonomous permeability.
Scientific research has found that human skin cells can only absorb substances with molecular weight less than 8000 daltons under normal circumstances, while hirudin has a very small molecular weight, only 7000 daltons, which can automatically and quickly penetrate into the deep skin and is easily absorbed and utilized by skin cells.
2. Promote blood circulation and repair acne marks.
Hirudin can promote blood circulation and repair scars.
Red acne marks are caused by skin inflammation after acne, and blood vessels do not contract after acne is eliminated.
Therefore, the blood-activating effect of hirudin is very targeted to the red acne marks left by acne.
3. Repair cells and nourish skin
Hirudin is a small molecule polypeptide with the characteristics of protein, but simpler than protein.
Its molecular weight is very small, it is easily absorbed by the skin and has high activity.
Can help repair cells and replenish nutrients to the skin.
4. Effectively penetrate and promote absorption.
Hirudin not only has a strong direct and independent penetration effect, but also can help other substances penetrate into the skin and promote skin absorption, which has a rare role in promoting penetration.
What is natural hirudin? What's the role? Natural hirudin is a natural substance extracted from leech saliva, which has a significant effect on the treatment of cardiovascular and cerebrovascular diseases.
It is an effective natural antithrombin substance, which has certain effects on dilating blood vessels, cleaning up blood waste and reducing blood viscosity.
Patented, it is an effective substance extracted directly from live leech.
Someone once told me about hirudin, but I didn't care. What exactly is hirudin? What's the effect? Hirudin is a small molecule protein (polypeptide) composed of 65-66 amino acids, which is one of the most active and researched components extracted from leech and its salivary glands.
Function: Hirudo is rich in hirudin, which has a strong inhibitory effect on thrombin and is the strongest natural specific inhibitor of thrombin found so far.
Hirudin has a strong inhibitory effect on coagulation and thrombosis, and has a broad application prospect in clinical treatment and prevention of various thrombosis.
It is precisely because hirudin has strong thrombolytic and anticoagulant effects, which can reduce blood viscosity, promote capillary recanalization, promote cell regeneration and repair hair follicles, enhance cell water retention function, shrink pores, enhance skin elasticity and prevent premature wrinkles. Long-term use can really make skin delicate, rosy and fair.
Extended data:
Application prospect of hirudin;
Medicine, like other natural sciences, has returned to its original point after thousands of years of reincarnation, and leech biotherapy, an ancient treatment method, is also considered as the basis of new medical technology.
Leech therapy can't be used as a substitute for microsurgery, but it can be used when the clinical conditions of patients don't allow long-term microsurgery or the microsurgical equipment fails or the microsurgery fails and complications occur.
Hirudin is widely collected in basic research and clinical application because of its high affinity and specificity for thrombin, and is considered as the strongest direct inhibitor of reversible thrombin.
After 2004, the US Food and Drug Administration recognized medical leeches as "medical institutions".
The European Union also recognizes that medical leeches are "medical commodities".
Nowadays, bloodsucking leeches are no longer hateful creatures, but lovely creatures that help treat diseases.
Because, after being bitten by leeches, the blood circulation becomes smooth.
Once a humble leech, leech is making great contribution to human health, and leech will be the best doctor to treat blood vessels in the future.
Baidu encyclopedia-hirudin
People's Network-Nanning High-tech Zone Helps Guangxi Hirudin Expand International Market
I want to ask what role hirudin has. Hirudin is a promising anticoagulant and blood stasis-removing drug, which can be used to treat various thrombotic diseases, especially venous thrombosis and disseminated vascular coagulation. It can also be used to prevent arterial thrombosis after surgical operation and thrombosis after thrombolysis or vascular reconstruction. Improve extracorporeal blood circulation and hemodialysis process.
In microsurgery, vascular embolization at anastomosis often leads to failure. Hirudin can promote wound healing.
Studies have also shown that hirudin can also play a role in tumor treatment.
It can prevent the metastasis of tumor cells and has been proved to be effective for fibrosarcoma, osteosarcoma, angiosarcoma, melanoma, leukemia and other tumors.
Hirudin can also be used in combination with chemotherapy and radiotherapy to enhance the curative effect by promoting blood flow in tumors.
Animal experiments and clinical studies show that intravenous or subcutaneous injection of hirudin has no obvious toxic and side effects. No matter acute or subacute toxicity test, it has no effect on blood pressure, heart rate, blood phase, bleeding time, blood chemical composition, respiratory system and allergic reaction. Generally, no specific antibody was found.
The semi-lethal dose LD5050mgAg is much larger than that used for treatment (1mgAg).
In particular, hirudin can be taken orally, which brings great convenience to medication.
Hirudin is relatively stable, trypsin and chymotrypsin do not destroy its activity, and some hydrolyzed fragments of hirudin still inhibit coagulation.
The role of blood enzymes may explain why oral leech extract is still effective.
In recent years, there have been many kinds of Chinese patent medicines with hirudin as the main component, such as antithrombotic tablets and Huoxuetong capsules, with an annual output value of tens of millions of yuan.
New drugs containing leeches are constantly being researched and introduced.
The production of recombinant leech polypeptide drugs by genetic engineering is expected to be realized in the near future, replacing hirudin or as an additive of anticoagulant and blood stasis-removing drugs.
As an injection for the treatment of cardiovascular diseases and tumors, further clinical research is needed.
Undoubtedly, the development of recombinant hirudin polypeptide drugs will bring great social and economic benefits.
So much for the introduction of the efficacy and function of hirudin. Thank you for taking the time to read the contents of this website. Don't forget to search for more information about the efficacy and side effects of hirudin.