Iron deficiency anemia, trauma, post-surgery, childbirth, some solid tumors, lymphoma, hemolytic anemia, acute or chronic blood loss, rheumatic fever, rheumatoid arthritis, nodular periarteritis , ulcerative colitis, localized colitis, tuberculosis, sarcoidosis, chronic lung abscess, osteomyelitis, etc.
The normal value of platelet count should be between 100-300. If the value exceeds 300, it means that the platelet count is high.
1. Platelet function defects: It has been clinically found that many patients with high platelets have defects in platelet function, including decreased adhesion and aggregation functions, decreased platelet factor III, decreased 5-hydroxytryptamine, and abnormal release function. situation, and some patients with thrombocytosis also have abnormal coagulation mechanisms and increased capillary fragility. Due to excessive platelets and the production of thromboxane by activated platelets, it is extremely easy to cause platelet aggregation and release reactions, which will cause the formation of microvessels. thrombus.
2. Too fast platelet production: Most patients with high platelets are caused by too fast platelet production. Mild thrombocythemia may be caused by the presence of plasma platelet stimulating factors that lead to excessive platelet production. Some patients have increased platelets after exercise, which is mostly caused by excessive release of platelets from storage pools such as the spleen and lungs. The production of platelets is controlled by hematopoietic factors, and the occurrence of thrombocytosis is related to the release of factors such as interleukins.
3. Secondary thrombocythemia: Secondary thrombocythemia is related to physiology, infection, bleeding, iron deficiency, tumors and the use of certain drugs. Among them, essential thrombocythemia is quite rare in children and adolescents. Infection is also the cause of thrombocytosis, especially acute infection, such as viruses, bacteria, mycoplasma, etc. Among them, respiratory tract infection is the most common, and infection may be accompanied by leukocytosis.
Remind everyone that the high platelet count is not too high, so you can rest assured that it may be an accidental condition of the body and not a disease. But if the platelet count is high and the number is relatively large, you can consult the relevant doctor in detail to see what causes the high platelet count, whether it will cause harm, whether treatment is needed, etc., so that you can avoid wrong treatment. Or a condition where the disease is ignored.