Extended data
1, used with caution by people with a history of lactic acidosis and elderly patients. Because this product may accumulate lactic acidosis, once it happens, it will lead to life-threatening Therefore, renal function should be monitored and the minimum effective dose should be given to reduce the risk of lactic acidosis.
2, fever, coma, infection and other stress states, surgery and the use of iodine-containing contrast media for inspection, should temporarily stop using this product, because it may lead to acute renal function deterioration. When this product is combined with sulfonylureas and insulin, it can cause hypoglycemia. Try to avoid drinking alcohol when taking this product. Easy to cause hypoglycemia or lactic acidosis. Use with caution in patients with poor liver function.
2. This product can interfere with the absorption of vitamin B 12, so it is recommended to monitor the blood picture. Allergic to this product, diabetic ketoacidosis, hepatic and renal insufficiency (serum creatinine exceeds 1.5mg/dl), pulmonary insufficiency, heart failure, acute myocardial infarction, severe infection and trauma, major surgery and clinical hypotension and hypoxia, alcoholism, vitamin B 12, folic acid deficiency, severe diabetic nephropathy, diabetic retinopathy, and so on.