Have you been taking sorafenib for more than a year?

I don't know how your patient is now. I wish him good luck! My father is sixty years old. He was diagnosed with advanced liver cancer on August 27th last year. At that time, there were no other symptoms except emaciation, and the diet was normal. The doctor judged that he had three months to live. He was immediately transferred to Nanjing People's Hospital for hospitalization. After examination, he found a tumor thrombus in the portal vein. Interventional therapy was performed immediately, and sorafenib was taken at the same time. The first and second interventional operations achieved good results, and everything was normal after operation. We also went out for a few short trips during the operation. During that time, we even occasionally forgot that our father was a terminal cancer patient, and there was a lot of emotion and happiness in the rare calm. Now I regret not going out a few times more. Three months later, in mid-June+February, 5438, when the third operation was about to be performed, the amount of ascites increased, abdominal pain appeared, total bilirubin could not be lowered, and jaundice could not be eliminated. The portal vein is severely embolized, so it is impossible to continue interventional surgery. Stop taking sorafenib on the doctor's advice. What you can do at this time is to be hospitalized for symptomatic treatment and try to alleviate his pain. He fell into a coma after 40 days in hospital and died five days later (1 March1).

After taking it for three months, my father didn't see much adverse reaction (occasional diarrhea, slight itching of hands, feet and heart). I can't evaluate the role of Sorafeni. If the survival time is prolonged by two months according to the doctor's judgment, I feel that the main role is intervention. Before taking it, we did some understanding, except for lung cancer patients who took it for more than one year, liver cancer patients had never seen it.

Liver cancer is the king of cancer. It's unfortunate, helpless and helpless to get this disease. It is suggested to intervene in the whole operation as much as possible, and be more careful during the operation to ensure the quality of life of patients as much as possible. Life cannot be prolonged, but quality can be improved.

In addition, among the patients in our ward, one patient can have the ninth interventional operation. He is a mid-term patient.

Good luck!