Who are the producers of human albumin?

List of enterprises producing human albumin 1 human albumin 10 %× 50ml Xi Anruike Biological Products Co., Ltd. 2 human albumin 10 %× 1 0%×50ml Xi Anruike Biological Products Co., Ltd. 3 human albumin 5 %× 200ml Xi Anruike Biological Products Co., Ltd. 4 human albumin 20 %× 50ml Xi 'an Anruike Biological Products Co., Ltd. 5 %× 40ml 6%10 %× 20ml 7% 25 %× 50ml 8% 5g/bottle (25ml, 20%) 9 human serum albumin 10g/ bottle (50ml, 20%) Hebei Daan Pharmaceutical Co., Ltd. 10 human albumin 12.5g(50ml)/ bottle Chengdu Rong Sheng Pharmaceutical Co., Ltd. 6543332g Lanzhou Institute of Biological Products 17 human albumin * 5g Beijing Tiantan Biological Products Co., Ltd. 18 human albumin */ 0g Beijing Tiantan Biological Products Co., Ltd. 19 human albumin * 5g Beijing Tiantan Biological Products Co., Ltd. 20 human albumin * 2g Beijing Tiantan Biological Products Co., Ltd. 2 1 0g Beijing Tiantan Biological Products Co., Ltd. 22 human albumin * Co., Ltd. 23 human albumin * 20%50ml Tangshan Hua Kai Biotechnology Co., Ltd. 24 human albumin 20%, 25ml/ bottle 25 human albumin from Green Cross (China) Biological Products Co., Ltd. 50m l/ bottle 26 human albumin from Green Cross (China) Biological Products Co., Ltd. 20%×50ml( 10g/ bottle, 20%) 27 human serum albumin from Zhejiang Haikang Biological Products Co., Ltd. 20%×25ml(5g/ bottle, 20 20%) Zhejiang Haikang Biological Products Co., Ltd. 29 human serum albumin 12.5g/ bottle (25%50ml) Hualan Biological Engineering Co., Ltd. 30 human serum albumin 20%25ml/ bottle Zhengzhou Haixing Banghe Biological Pharmaceutical Co., Ltd. 32 Hualan Bioengineering Co., Ltd. Human albumin 20% 10ml/ bottle Zhengzhou Haixing Banghe Biopharmaceutical Co., Ltd. 33 human albumin 2g/ bottle (10%20ml). Hualan Bioengineering Co., Ltd. 34 human serum albumin 10g Henan Zhongtai Pharmaceutical Co., Ltd. 35 human serum albumin 2g Henan Zhongtai Pharmaceutical Co., Ltd. 36 human serum albumin 20%50ml/ bottle Zhengzhou Haixing Banghe Biological Pharmaceutical Co., Ltd. 37 human serum albumin 5g Henan Zhongtai Pharmaceutical Co., Ltd. 38 human serum albumin 10g/ bottle (1kloc-0/ 00ml) 39 Hualan Human Serum Albumin Ltd. 5g/ bottle (20%25ml) 4 1 Hualan Biotechnology Co., Ltd. Human Serum Albumin * 20%25ml 42 Tangshan Hua Kai Biotechnology Co., Ltd. Human Serum Albumin 10%, 20ml/ bottle 43 Human serum albumin of Wuhan Institute of Biological Products 20% 10ml 44 Human serum albumin of Wuhan Ruide Biological Products Co., Ltd., Ltd. 20%25ml/ bottle 45 Wuhan Institute of Biological Products Human Albumin 20%50ml/ bottle 46 Wuhan Institute of Biological Products Human Albumin 10%5g/ bottle 47 Wuhan Institute of Biological Products Human Albumin 10%, 10g/ bottle, 48 Wuhan Institute of Biological Products 20%. The content of 50ml 10g/ bottle of 50 people in Wuhan Reed Bio-Pharmaceutical Co., Ltd. is 5 1, and the albumin concentration of 52 people in Guhan Ziguang Bio-Pharmaceutical Co., Ltd. is 10%. 5g/ bottle Ziguang Guhan Bio-pharmaceutical Co., Ltd. 53 human albumin 20%25ml Wuhan Ruide Bio-products Co., Ltd. 54 human albumin * 10g/ bottle Changchun Bio-products Research Institute 55 human albumin * 5g/ bottle Changchun Bio-products Research Institute 56 human albumin 25%25ml(5g/ bottle) Hualan Bio-engineering (Suzhou) Co., Ltd. 57 human albumin * 20%. Kloc-0/0g/ bottle) 58 human serum albumin from Nanjing Huachen Bioengineering Co., Ltd. * 25ml bottle 6 1 200g/L 10g/ bottle 62 human serum albumin from Jiangxi Boya Biopharmaceutical Co., Ltd. and 63 human serum albumin from 10g xi Antianhui Blood Products Co., Ltd. Bottle xi An Tianhui Blood Products Co., Ltd. 64 human serum albumin 20%, 5g/ bottle Xi An Tianhui Blood Products Co., Ltd. 65 human serum albumin * 20%x65438 Co., Ltd. * Chongqing Yi Tuo Biopharmaceutical Co., Ltd. 67 human serum albumin 20% x25ml * Chongqing Yi Tuo Biopharmaceutical Co., Ltd. 68 human serum albumin 20%x50ml Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd. 69 human serum albumin 5g 20%, Chengdu Rong Sheng Pharmaceutical Co., Ltd. 70 human serum albumin 10g Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd. 7 1 20% human serum albumin10g Chengdu Rong Sheng Pharmaceutical Co., Ltd. 72 human serum albumin * 10g Shanghai Xinxing Pharmaceutical Co., Ltd. 73 human serum albumin * 12.5g, 50m l serum albumin of 74 people from Shanghai Laishi Blood Products Co., Ltd. * 2g, serum albumin of 75 people from Shanghai Laishi Blood Products Co., Ltd. 40ml * serum albumin of 76 people from Shanghai Xinxing Pharmaceutical Co., Ltd. 50ml * 5g, serum albumin of 78 people from 50ml Co., Ltd. 2g, serum albumin of 79 people from Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd. * 20%50ml Shandong Miqile Biological Products Co., Ltd. 80 human albumin * 20% 10ml Shandong Miqile Biological Products Co., Ltd. 8 1 human albumin * 10%50ml Shandong Miqile Biological Products Co., Ltd. 82 human albumin * 10%20ml Co., Ltd. */kloc. Kloc-0/00ml serum albumin of 84 people from Shandong Michele Biological Products Co., Ltd. * 20%25ml serum albumin of 85 people from Shandong Michele Biological Products Co., Ltd. * 20%50ml( 10g/ bottle). 86 human serum albumin of Shanxi Kangbao Biological Products Co., Ltd. * 20%25ml(5g/ bottle) 87 human serum albumin of Shanxi Kangbao Biological Products Co., Ltd. * 20% 10ml(2g/ bottle) 88 human serum albumin of Shanxi Kangbao Biological Products Co., Ltd. * 100g/L2g/ bottle 89 human blood of Harbin Shi Heng Bioengineering Pharmaceutical Co., Ltd. Kloc-0/0g/ bottle, 5g/ bottle Co., Ltd. 9 1 human albumin 200g/L5g/ bottle Shenzhen Wei Wu Guangming Biological Products Co., Ltd. 92 human albumin 200g/L2g/ bottle 93 human albumin from Shenzhen Wei Wu Guangming Biological Products Co., Ltd. 100g/L5g/ bottle 94 human albumin from Shenzhen Wei Wu Guangming Biological Products Co., Ltd. Kloc-0/0g/ bottle 95 human albumin from Guangdong Weilun Biopharmaceutical Co., Ltd. 20%50ml Co., Ltd. 97 human albumin * 20%25ml Guangdong Baiyi Pharmaceutical Co., Ltd. 98 human albumin * 20%50ml Guangdong Baiyi Pharmaceutical Co., Ltd. 99 human albumin 20%25ml5g/ bottle Sanjiu Group Zhanjiang Development Zone Sara Pharmaceutical Co., Ltd. 100 human albumin/ Kloc-0/00g/L2g/ bottle Shenzhen Wei Wu Guangming Biological Products Co., Ltd. 10 1 human albumin 100 Co., Ltd. 100g/ bottle Shenzhen Wei Wu Guangming Biological Products Co., Ltd. 105 human albumin * 20g, (20 100ml) Shanghai Lai Shi Blood Products Co., Ltd. 106 human albumin * 5g Liaoyang Blood Science and Technology Branch of Guangxi Beisheng Pharmaceutical Co., Ltd.10g Liaoyang Blood Science and Technology Branch of Guangxi Beisheng Pharmaceutical Co., Ltd. 65438Ltd.10. 0 human albumin 20%, 5g/ bottle Haikou Shengbao Biological Products Co., Ltd.1kloc-0/human albumin 20%, 2g/ bottle Haikou Shengbao Biological Products Co., Ltd.1/2 human albumin 20%, 10g/ bottle Haikou Shengbao Biological Products Co., Ltd. 1 13 human albumin 20%(50ml Anhui Daan Biological Products Pharmaceutical Co., Ltd.15 human albumin 20%(25ml:5g) Anhui Daan Biological Products Pharmaceutical Co., Ltd./kloc-0. 2g Shanghai Institute of Biological Products 1 17 Human Albumin * 5g Shanghai Institute of Biological Products 1 18 Human Albumin * 10g Shanghai Institute of Biological Products 65 Human Albumin Bottle of Liuzhou Biological Products Branch of Guangxi Beisheng Pharmaceutical Co., Ltd.12/KLOC-0. 20%×50m l/ bottle 10g/ bottle human albumin bottle of Liuzhou Biological Products Branch of Guangxi Beisheng Pharmaceutical Co., Ltd. 122 * 20%× 10ml/ bottle 2g/ bottle 123 human albumin bottle * and Shanghai Xinxing Pharmaceutical Co., Ltd./kloc- Kloc-0/0g, 50ml Shanghai Laishi Blood Products Co., Ltd. 126 human albumin 10%50ml5g/ bottle Sanjiu Group Zhanjiang Development Zone Sara Pharmaceutical Co., Ltd. 127 human albumin 10%20ml2g/ bottle Sanjiu Group Zhanjiang Development Zone Sara Pharmaceutical Co., Ltd. 6544 Co., Ltd. 3 1 human albumin 50g/L 12.5g/ bottle Chengdu Rong Sheng Pharmaceutical Co., Ltd. 132 human albumin 50g/L 5g/ bottle Chengdu Rong Sheng Pharmaceutical Co., Ltd. 133 human albumin 50g/L 2g/ bottle Chengdu Rong Sheng Pharmaceutical Co., Ltd. 134 human albumin. L 50ml Harbin Shi Heng Bioengineering Pharmaceutical Co., Ltd. 65 Co., Ltd. * 2g/ bottle 138 Guangxi Beisheng Pharmaceutical Co., Ltd. Liaoyang Blood Technology Branch 20%, Xinjiang An Deyu Bioengineering Co., Ltd. 10g human albumin 20%, Xinjiang An Deyu Bioengineering Co., Ltd. 5g human albumin 140 human albumin/ Kloc-0/2.5g/ bottle Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd. 14 1 bottle Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd. Green Cross (China) Biological Products Co., Ltd. 50ml/ bottle +044, Hebei Daan Pharmaceutical Co., Ltd. 2g/ bottle +000ml/ bottle/kloc-0. Bottles of human serum albumin from Hebei Daan Pharmaceutical Co., Ltd. 20%, 12.5g/ bottle of human serum albumin from Hebei Daan Pharmaceutical Co., Ltd. 65438.150 5g/ bottle, 10%, 50ml of human serum albumin from Hebei Daan Pharmaceutical Co., Ltd. was separated and extracted from the plasma of healthy people, and human serum albumin preparations mainly contained 5% and 5%. Human albumin plays an important role in increasing circulating blood volume and maintaining plasma osmotic pressure, but besides maintaining colloid osmotic pressure's volume therapy, other important functions are neglected: substance binding and transport, coordinating vascular endothelial integrity and permeability, antioxidation, anti-inflammation, protecting blood cells, regulating coagulation, and repairing injuries. Clinical indications for rational use of albumin include shock caused by hemorrhagic trauma and burn, increased intracranial pressure caused by brain edema and brain injury, edema or ascites caused by cirrhosis and nephropathy, prevention and treatment of hypoproteinemia and neonatal hyperbilirubinemia, and adjuvant treatment of cardiopulmonary bypass, burn, hemodialysis and adult respiratory distress syndrome. Human albumin does help some critically ill patients, but its curative effect is often exaggerated by some people. There is no evidence to support its clinical application in supplementing nutrition, treating nephrotic syndrome, chronic liver cirrhosis and enhancing immunity. Although human albumin has the above pharmacological effects, 5% and 20% products with different specifications have their own characteristics and different clinical applications. Now, compare the main differences between the two specifications. 1. Table of Composition and Traits Difference 1, 5% and 20% Comparative Analysis of Composition and Traits: The concentration of 5% 20% albumin is 5g/100 ml 20g/100 ml, with the highest active monomer content, the highest polymer content and the lowest sodium octanoate content of 0.004m0.01respectively. 0.02M sodium acetyltryptophan 0.004M 0.0 16M/0.02M light yellow note: (1) monomer is the active form of human serum albumin because of its physiological function and therapeutic effect. The higher the monomer content in albumin solution, the higher the therapeutic performance; On the contrary, the higher the polymer content, the lower the therapeutic performance. Therefore, the preparation and verification of human albumin in China's "Regulations on Biological Products" clearly stipulates that the polymer content of human albumin products must be ≤ 5%. Basic research has confirmed that the monomer content of human serum albumin is negatively correlated with the solution concentration, that is, the higher the albumin solution concentration, the lower the monomer content. In the production and preparation of human albumin, compared with the common 20% concentration and 5% solution, the extraction and purification technology of protein is more demanding. The monomer content based on 5% albumin is higher than that of 20% albumin. Therefore, in various clinical uses of albumin, 5% human albumin solution has irreplaceable high therapeutic value. (2) Sodium octoate and sodium acetyltryptophan are internationally recognized stabilizers of albumin solution, which can increase the thermal stability of albumin solution and make it pass the virus inactivation procedure in the production process-pasteurization without coagulation and denaturation. Because 5% albumin solution has a high monomer concentration, the experiment proves that its thermal stability is better than that of 20% solution, so relatively few stabilizers can be added in the production and preparation process. Second, the difference of pharmacological effects. Albumin in blood can maintain 70 ~ 80% effective colloid osmotic pressure, and 1 g albumin can recover about 18mL of fluid from tissue fluid. 5% is isotonic albumin, and colloid osmotic pressure = colloid osmotic pressure of equal volume plasma, which is similar to plasma to coordinate the exchange of fluids inside and outside blood vessels, thus balancing the income and expenditure of fluids inside and outside blood vessels, expanding blood volume without reducing interstitial fluid, and effectively protecting the internal environment stability of tissues and organs. 20% is hypertonic albumin, and colloid osmotic pressure = 4 times the colloid osmotic pressure of the same volume of plasma, so that the amount of tissue fluid returned to the blood vessels is greater than the amount of fluid leaked from the blood vessels, and a large amount of tissue fluid is returned to the blood vessels, which reduces the amount of tissue fluid while expanding the blood volume and effectively relieves the edema of tissues/organs. III. Differences in clinical use Table 2, 5% recommends clinical departments for room indications ☆ Early correction of hypoproteinemia during and after operation ☆ Organ perfusion fluid during liver transplantation ☆ Cardiac surgery ☆ Early correction of hypoproteinemia during and after operation ☆ Pipeline priming fluid during cardiopulmonary bypass ☆ "Happy" operation ☆ Cardiac paralysis fluid in emergency, ICU, operating room, anesthesia department, operating room ☆ Early hypovolemia with or without partner. ) Burn Department ☆ Early blood volume supplement and correction of hypoproteinemia in large area burn Other intensive care departments ☆ Correction of hypoproteinemia ☆ Large dose plasma exchange ☆ Red blood cell infusion dilution, etc. Table 3, 20% recommended for clinical use, transplantation department ☆ correct hypoproteinemia before and after operation, eliminate ascites ☆ liver failure (MARS et al. ) ☆ Gastroenterology, Infectious Diseases ☆ Cirrhosis ascites ☆ Acute liver failure (MARS, etc. ) ☆ Neurosurgery ☆ Acute craniocerebral trauma, brain edema, etc. ICU, Respiratory Department ☆ Acute pulmonary edema and adult respiratory distress syndrome (ARDS) Burn Department ☆ Burn edema pediatrics ☆ Newborn hemolytic disease (hyperbilirubinemia) emergency department ☆ Non-specific antidote for acute poisoning and other critical departments ☆ Correcting hypoproteinemia ☆ Eliminating edema As for which manufacturer sells well, it depends on which province and city you are in.