But, dear, what I want to say is, after opening, don't use any cosmetics and articles with therapeutic effect unless they are put in the refrigerator, or I suggest you use them up within one year. After opening the lid, it is no longer airtight, which will breed bacteria, especially if you still have acne ... If it is more than one year, it is not recommended that you continue to use it. I wish you good skin ~O(∩_∩)O!