Advantages of blastocyst culture
1. Three-day-old embryos cannot reach the uterus by themselves under natural conditions. Embryo transfer will definitely reduce the vitality of embryos, and blastocyst transfer is more in line with physiological conditions than cleavage embryo transfer.
2. The embryo was transplanted on the third day. At this time, the uterus has not recovered from the stimulation of ovulation, which is not conducive to embryo implantation. However, blastocyst transplantation has better synchronization with uterus and higher acceptance of uterus.
3. Prolonging culture to blastocyst stage can help us to screen out embryos with better development potential. The pregnancy rate of blastocyst is higher than that of cleavage stage embryo, which is more suitable for single embryo transfer. Therefore, a series of subsequent complications caused by multiple births can be avoided.
4. Blastocysts will be more tolerant to freezing and thawing, that is, more "freeze-resistant", and the survival rate after detoxification will be higher.
Will keeping the capsule lead to "no eggs available"?
Some embryos are few in number and poor in quality, and some elderly patients are very likely not to raise cysts. As a result, these patients have no embryos to transplant. Does this mean that embryos are wasted because they keep cysts? In fact, blastocyst culture eliminated some embryos with relatively poor development potential. Even if we don't take care of these embryos, there is a great possibility of implantation and abortion after transplantation.
Who is suitable for keeping capsules?
1. When the woman is relatively young, the ovarian reserve is relatively good and the number of eggs obtained is ideal. The quality and quantity of three-day embryos are very high. Usually there will be at least two high-quality embryos on the third day. In this case, the "risk of embryo uselessness" after blastocyst culture will be relatively small.
2. The uterine environment of patients with bilateral proximal tubal obstruction or bilateral salpingectomy is more suitable for blastocyst transplantation.
3. Women who repeatedly fail to plant can screen out embryos through blastocyst culture, which effectively reduces the possibility of failure caused by embryo problems.
4. For women who are afraid of ectopic pregnancy, blastocyst transplantation can appropriately help patients reduce the incidence of ectopic pregnancy.
For parents who want to be test-tube babies, they must have heard of the technique of retaining cysts, because when doing test-tube babies in China, doctors will let patients decide whether to retain cysts, because for test-tube babies, retaining cysts is an extra link, that is, embryo transfer can be carried out without retaining cysts, or embryo transfer can be carried out after retaining cysts, so whether test-tube babies need to retain cysts is a concern of all patients!
What is a blastocyst?
Blastocyst refers to a fully developed embryo, which is the last stage of embryo culture in vitro. It usually forms on the fifth day after fertilization. Under natural conditions, embryos can be transplanted into the uterus in the form of blastocysts, with a high success rate.
What are the benefits of keeping capsules?
1. In chromosome screening, there are many blastocyst cells, which is convenient for embryo biopsy to obtain more cells and make embryo genetic detection more accurate.
2. There are a large number of blastocysts, especially the outer cells, which have strong repair ability after freezing and resuscitation, and have little effect on embryo development potential.
3. Blastocyst transfer often only needs to transfer one embryo, which can reduce the occurrence of multiple pregnancies and avoid unnecessary trouble of fetal reduction.
4. The ectopic pregnancy rate of blastocyst transfer is lower than that of embryo transfer in cleavage stage on the third day.
5. Blastocyst transplantation is synchronous with the development of endometrium, which is more in line with the physiological state.
6. The developmental potential of blastocyst on the third day is higher than that of cleavage embryo, and its transplantation success rate is also higher.
What is the standard of eye bags for IVF?
1. Equipment and technical support are available, so as to ensure that after sperm and eggs are taken out, there will be no pollution and external damage during fertilization.
2. In order to have enough fertilized embryos, raising a pouch is an unknown adventure. In order to avoid risks as much as possible, the number of high-quality embryos needs to reach more than 4.
3, good physical conditions, the woman must have enough physical conditions to support the implantation of the gestational sac into the uterus to ensure the normal implantation and normal development of the gestational sac.
Do you want to keep a bag or not?
If blastocysts are not preserved, the implantation rate of embryos in the maternal uterus is much lower than that of blastocysts, because only embryos with good development potential can form blastocysts, which means that the process of embryo forming blastocysts is a competition of survival of the fittest, so blastocyst transplantation will greatly improve the rate of IVF.
Hello, whether to make a test tube varies from person to person, but sometimes, the doctor will let the patient decide for himself, which is determined by the particularity of the behavior of keeping capsules. Capsule rearing is an extra and unnecessary part of IVF, that is to say, embryo transfer can be carried out without capsule rearing, and blastocyst transfer can be carried out after capsule rearing. Therefore, there is a trade-off between keeping capsules and not keeping them.
1, capsule transplantation is more suitable for uterine environment. If it is a three-day cleavage embryo transfer, the embryo will not be implanted until the fifth day, so the embryo is still in a free state at this time. At this time, when transplanted into the uterus, the environment does not adapt, and it may drift to the fallopian tube, forming an ectopic pregnancy.
2. Most nutritional capsules are single transplantation. Because the embryos in the three-day cleavage stage are extremely fragile, in order to increase the success rate, doctors often carry out double embryo transfer or even triple embryo transfer. If multiple embryos are successfully implanted at the same time, embryo reduction is needed, which will also bring risks. Because of the high quality of embryos, intracapsular embryo transfer often only needs monogamy.
3. The success rate of capsule transplantation is higher. The success rate of embryo transfer in three-day cleavage stage is very low, while the success rate of blastocyst transfer is more than double.
4. Feeding capsules may face the situation that no capsules are available. Blastocyst transplantation does have advantages, but not all test-tube families can choose to raise blastocysts. Especially in families with poor sperm quality and few eggs, because there are few embryos cultivated by in vitro fertilization, it may lead to the embarrassment that they have not passed the "test" after fertilization.
Therefore, whether to choose capsule transplantation depends on different people. In the process of test tube, consult the doctor more and make a decision according to the doctor's advice. In addition, in order to improve the vitality of sperm and eggs, and finally cultivate more high-quality embryos, test-tube couples should take relevant measures such as exercise, rest and health care before the test tube to make a test tube with good physical quality.
Blastocyst refers to the embryo that produces blastocyst fluid and blastocyst cavity inside, which is the last stage of embryo culture in vitro and usually forms on the 5 th to 7 th day after fertilization. In the process of the third generation of IVF, blastocyst culture is a necessary condition for subsequent gene detection and embryo transfer.
When the embryo develops to the blastocyst stage, doctors can extract cell samples from the blastocyst shell (i.e., trophoblast) for genetic testing, diagnose and screen whether the embryo has corresponding genetic diseases and chromosomal abnormalities, so as to select healthy blastocysts for transplantation. Because the sampled cell sample is extracted from the trophoblast, it will not cause too much damage to the inner cell mass of the blastocyst and affect the normal development of the embryo. However, if the morula is sampled by cytogenetics, it may damage the foundation of embryo development and the genetic information obtained may not be accurate enough. Furthermore, because blastocysts survive longer than morulae in vitro, the number of dividing cells is much more; Compared with morula, it is much larger and more mature, and the pregnancy rate of transplanted morula can be about twice as high as that of transplanted morula. Internationally recognized, blastocyst is the most suitable embryo for transplantation, and also the embryo with the highest clinical pregnancy rate after transplantation.
However, high success rate is naturally accompanied by high risks. It is true that the pregnancy rate of transplanted blastocysts is very high, but there is a cruel reality of raising blastocysts. That is to say, it is possible that many people in the process of raising cysts, even if there are a large number of initial fertilized eggs or even embryos, will eventually not appear cysts because of embryo quality or chromosome abnormalities.
In fact, we have to admit that the advantages of blastocysts in prenatal and postnatal care and improving pregnancy rate after genetic testing are incomparable to morula. If a morula has no potential to develop into blastocysts with the support of many medical technologies in vitro, why should we believe that it can develop into blastocysts and grow into healthy babies after being transplanted into the mother's uterus? Choosing to transplant morula may have more transplant opportunities, but there are also more chances of failure, which will bring more pressure and physical burden to yourself.
In fact, it is better to pursue the quality of embryos than the number of embryos. At present, with the continuous progress of assisted reproductive technology, the difficulty of cultivating fertilized eggs into blastocysts is actually the same as that of cultivating morulae, and there is no technical difficulty. Therefore, in the process of IVF, if conditions permit, it is best to culture the embryo to blastocyst form before transplantation.
You can decide according to your own situation. If there are many eggs, you can freeze a few eggs. Then the sac is raised and the embryo is frozen after success. In this way, the follow-up hands are all done, so you don't have to worry about the test tube this time.
The term "blastocyst culture", which is often used in clinic, actually refers to blastocyst culture, that is to say, embryos cultured in vitro until the third day of cleavage continue to be cultured until the fifth to sixth day to become blastocysts. Clinical data prove that blastocyst transfer can improve the implantation rate of embryos, reduce the pregnancy loss rate, shorten the pregnancy time and reduce the mental stress and psychological burden of patients. On the other hand, in laboratory embryo culture, embryo culture experts believe that in the process of obtaining blastocysts in vitro, we can learn more about the development information of embryos, which is also conducive to selecting embryos for single embryo transfer (SET). To sum up, the advantages of blastocyst culture are obvious. Yi Rui yeast
Whether you need blastocysts depends on your specific situation! For example, how many eggs have been taken and how many fresh embryos have become!
The most straightforward and universal fact is that,
Fresh embryos are easier to be cultured successfully, but the pregnancy rate after transplantation is lower than that of blastocysts!
The success rate of fresh embryo culture to blastocyst is low, but the success rate of pregnancy after blastocyst transplantation is high!
I wish the majority of infertile patients a dream of seeking children in yen!
The situation of raising cysts varies from person to person. For example, if a chromosome abnormality is identified, 5 or 23 pairs of chromosomes need to be screened. Or want to improve the singleton pregnancy rate, multiple embryos, or other conditions.
A blastocyst is an embryo cultured to the fifth day after fertilization, and an embryo that has formed hundreds of cells is called a blastocyst. The implantation rate is 50% higher than that of the embryo on the third day, which can effectively avoid the occurrence of ectopic pregnancy.
In addition, some embryos will lose too much during feeding and may survive if transplanted into the uterus.
IVF assisted reproductive technology has helped more and more infertile families realize their dream of seeking children. So, do you need sample bags in the process of IVF?
In the process of embryo culture, if there are a large number of embryos, it is suggested to keep blastocysts, because blastocysts can improve the success rate of IVF. If not, the implantation rate of embryos in the uterus of expectant mothers is much lower than that of blastocysts, because only embryos with good development potential can form blastocysts, which means that the process of embryo formation is a competition of survival of the fittest, so blastocyst transfer will greatly improve the pregnancy rate in vitro. If the number of embryos is small, it is recommended not to raise cysts. In that case, there may be no transplantable embryos in the end, and all of them will be screened. Specifically, according to the advice of hospital doctors, we will decide whether to raise capsules or not.
I hope the answer can help you. If you have any questions, please consult Taimei Baby Atomic Consultant.