Why is the therapeutic effect of liver cancer poor? These three reasons make liver cancer a well-known "king of cancer"
To improve the therapeutic effect of liver cancer, we should start with the prevention and treatment of liver cancer. One is the early prevention of liver cancer pathogenic factors, such as:
Second, do a good job in early screening of liver cancer: for middle-aged people over 40 years old with the above-mentioned high-risk factors and family history of liver cancer, perform liver ultrasound examination and +AFP detection. Do early examination and early treatment.
Third, the comprehensive treatment of liver cancer:
In a word, the poor curative effect of liver cancer is related to the fact that liver cancer is buried deep in the abdominal cavity, with strong compensatory ability and difficult clinical manifestations in the early and middle stages, and also related to the early intrahepatic metastasis of liver cancer. In order to improve the therapeutic effect of liver cancer, the key lies in the prevention and treatment of liver cancer.
This statement is really one-sided and dangerous, and it is easy for patients with liver cancer to lose confidence and give up treatment. China is a big country with liver cancer. We have accumulated a lot of successful experience in treating liver cancer and cured many patients with liver cancer. An old patient of mine was diagnosed with liver cancer in 2007, and he was still healthy after the operation. In the field of tumor, there are four academicians in the single subject of liver cancer: Tang Zhaoyou, Wu,,,. He is very accomplished in surgical treatment of liver cancer and liver transplantation for liver cancer.
The reason why some people say that "liver cancer is basically incurable as long as it is detected"? I think in many cases, because the mortality rate of liver cancer is too high, most liver cancers have no chance of surgery, and many operated liver cancers die after recurrence. Indeed, 85% of patients with liver cancer in China are complicated with chronic hepatitis and cirrhosis, resulting in poor liver function compensation. The tumor resection rate was only maintained at 10%~40%, and about 50% patients recurred after operation.
However, it is really wrong to say that liver cancer can't be cured. In addition to surgery and interventional therapy, liver cancer is now being studied in the field of targeted drugs. There will be more and more treatments for liver cancer, and the survival time will be longer and longer. So, how should liver cancer be treated? First of all, we must accurately stage:
The first stage: surgical resection as much as possible. For those who cannot be resected for some reasons, liver transplantation or local non-resection is feasible. Adjuvant treatment should be added as appropriate after operation; The second stage: comprehensive treatment such as surgery (resection or non-resection) and/or radiotherapy and intra-arterial administration; Stage III: Biotargeting or traditional Chinese medicine treatment is the main treatment, and Child-Pugh grading A-B is feasible for systemic chemotherapy. Don't ignore the role of traditional Chinese medicine in the treatment of liver cancer.
Generally speaking, surgical resection is the most effective method to treat early liver cancer at present, and the postoperative 1 year, 3-year and 5-year survival rates are 80%~920% respectively.
60%~86% and 40%~75%. Liver transplantation is another way to cure liver cancer. For small hepatocellular carcinoma that cannot be resected due to severe liver cirrhosis, such as a single tumor with a diameter of 2-5 cm or the sum of multiple tumors with a diameter of less than 3 cm, liver transplantation can be selected, and the survival rate after 5 years can reach 78%-80%. However, due to its strict indications, difficult donor, high treatment cost and long-term use of anti-rejection drugs after operation, liver transplantation for liver cancer is not smooth.
Liver cancer refers to the malignant tumor of the liver, which can be divided into primary liver cancer and secondary liver cancer. Primary malignant tumor of liver originated from epithelial or mesenchymal tissue of liver. The former is called primary liver cancer, which is a malignant tumor with high incidence and great harm in China. The latter is called sarcoma, which is rare compared with primary liver cancer. Secondary liver cancer refers to liver cancer transferred from other parts, which is usually multiple. China is a big country with liver cancer.
Etiology of liver cancer 1. Virus infection: Hepatitis B virus infection is the most common cause of liver cancer in China. China is a big country with hepatitis B, and it develops into liver cancer 10 years or even longer after virus infection.
2. Aflatoxin: Currently recognized carcinogen.
3. Liver cirrhosis and drinking: Liver cirrhosis is also a high risk factor for liver cancer.
4. Liver fluke: Long-term liver fluke causes liver cell canceration.
Early clinical manifestations of liver cancer: there are no obvious symptoms in the early stage of liver cancer, which is also the main reason why liver cancer is difficult to find.
Mid-late stage: Common clinical manifestations include liver pain, abdominal distension, anorexia, fatigue, emaciation, progressive hepatomegaly or upper abdominal mass. Some patients have low fever, jaundice, diarrhea and upper gastrointestinal bleeding; Acute abdomen occurred after the rupture of liver cancer.
The treatment of liver cancer is the key to improve the curative effect, and individualized comprehensive treatment is carried out according to different stages of liver cancer. Treatment methods include surgery, hepatic artery ligation, hepatic artery chemoembolization, radio frequency, freezing, laser, microwave, chemotherapy and radiotherapy.
The malignant degree of liver cancer is high and the therapeutic effect is relatively poor. The key lies in early detection and early treatment.
As an expert in hepatobiliary surgery, I can tell you responsibly that this statement is completely wrong.
There are many ways to find liver cancer:
1, found during physical examination
2, hepatitis B patients, found during regular inspection.
3, because of other diseases to the hospital, found during hospitalization.
4. I felt unwell and went to the hospital for examination.
5, liver tumor rupture led to bleeding, when sent to the hospital found that liver cancer rupture.
Of course, there are other ways to find liver cancer.
Analyze the above methods for the time being.
As can be seen, in the above manner,
1, 2, 3 are often discovered in the early stage.
Fourth, because of discomfort, such as a dull pain in the right upper abdomen, this time may indicate that the liver tumor has grown up.
Fifth, the tumor has ruptured, that is to say, the ruptured tumor cells have spread to the whole stomach, and even treatment can not clean up the tumor.
The treatment of liver cancer is often decided according to the stages of liver cancer. Barcelona staging is commonly used at present.
The picture above shows the common stage of liver cancer.
The size and number of tumors are very important for the staging of liver cancer. Many people find liver tumors in health checkups, which are often relatively small. I once met an old man who was diagnosed with a liver tumor when he went to the countryside for a physical examination in a township health center. It is only about 3.2cm in size and belongs to small liver cancer. He had a minimally invasive resection on our side, and now everything is fine. It has been more than 1 year since the operation, and there is no sign of recurrence.
What if there is a dull pain in the abdomen? The result is often: the longer the tumor, the bigger it is.
Why do tumors tend to get bigger when there is abdominal pain?
Because this kind of pain is felt by the nerves in the capsule on the surface of the liver, when the tumor is relatively large, it will stimulate the capsule and cause pain. Therefore, when there is abdominal pain, it often means that the tumor is relatively large. Because liver cancer has the characteristics of intrahepatic vascular invasion and intrahepatic metastasis, the bigger the tumor, the easier it is to invade intrahepatic blood vessels and intrahepatic metastasis, and the therapeutic effect is definitely not as good as that of small liver cancer.
Back to this topic, the prognosis of liver cancer, that is, how long you can live with liver cancer, is directly related to whether it is early or late when liver cancer is discovered, and once it is discovered, it is not incurable.
It used to be said that liver cancer is the "king of cancer". With the deepening of the research on liver cancer, there are more and more treatments for liver cancer.
For liver cancer, we emphasize comprehensive treatment (MDT), including: 1, surgery (open or minimally invasive); 2. Interventional therapy (before and after operation); 3, radiofrequency ablation (the effect of small liver cancer is even comparable to surgery); 4. Targeted therapy (sorafenib, repaglinide, PD- 1, etc. ).
Therefore, as long as the tumor is not full, or as long as it has not metastasized to other organs, there are still many methods to choose from for the treatment of liver cancer, and sometimes the treatment of advanced liver cancer will achieve unexpected good results.
Remember: physical examination is very important. If found in time, cancer can be killed in the cradle.
Liver cancer is one of the common malignant tumors in China. Because patients with liver cancer are asymptomatic in the early stage, most people lack the awareness of liver cancer screening, so they often go to the doctor when symptoms appear. At this time, the disease has often reached the advanced stage. The survival time of advanced liver cancer is only 3-6 months, and the prognosis is poor.
So, after the diagnosis of liver cancer, there is no hope of treatment? Below, I will give you a popular science about the treatment of liver cancer and what conditions it is suitable for.
First, the lesion is confined to the liver. If the liver function is normal or slightly abnormal (specifically, it needs to be evaluated by the attending physician), surgical resection, liver transplantation, ablation (radio frequency, microwave, freezing, anhydrous alcohol), hepatic artery interventional embolization, radiotherapy and other local treatment methods can be selected, alone or in combination.
Second, the lesion metastasized to hilar lymph nodes. You can choose to combine interventional therapy with radiotherapy (Professor Zeng from the Department of Radiotherapy of Zhongshan Hospital affiliated to Fudan University and Professor Wang from the Department of Radiotherapy of Peking University Cancer Hospital have rich experience in this field).
Third, the lesion metastasized to organs other than the liver. If there are a few isolated metastases, local treatment can be used to treat liver lesions, and radiotherapy can be given to a few isolated metastases. If it is extensive metastasis, the prognosis is very poor. According to the patient's physical condition, chemotherapy or targeted therapy can be tried.
Traditional Chinese medicine is very reasonable, "cure disease before it happens", so it is more important to prevent liver cancer than to treat it.
China is a big country with hepatitis, and most liver cancers occur on the basis of hepatitis and cirrhosis. It is suggested that patients with hepatitis B and C need to regularly detect the virus replication and follow the antiviral treatment scheme prescribed by hepatologists to try to slow down the progress of liver cirrhosis and liver cancer. At the same time, avoid long-term heavy drinking, reduce the intake of aflatoxin-containing food, and start from the details of life to actively prevent liver cancer. Good wishes!
No, I have a patient who said it was several years after liver cancer surgery. It is still related to staging and typing. Every tumor is like this. Early cancer has a good prognosis, but late cancer is almost worse. This is a recognized thing. Just like putting out a fire, it was found to have been put out as early as a small fire, so personal safety and property safety are fine. If the fire is too big, many things will be burned. At this time, even if the fire is put out, many things have been damaged and the house is easy to collapse. Compared with people, in the later stage, the human body is already very fragile, the functions of various organs will be affected, and death will be quick.
The horror of liver cancer lies in its high incidence rate, which is the second highest in China. Secondly, it is often found very late, and the symptoms of liver cancer are often in the middle and late stages, and the opportunity for surgical treatment is missed. Just re-emphasize the importance of physical examination. Nowadays, physical examination is popular, and many people find tumors early, and early surgery has a relatively good prognosis. I study Chinese medicine, so I will definitely emphasize the role of disease prevention. Prevention of liver cancer is very important. The main cause is hepatitis, so screening and treatment of hepatitis; There are also drinking, Aspergillus flavus infection, abstinence from alcohol and pickled products, weight control, good mood, and learning to release stress.
Praise is an important organ to promote the liver to belong to human beings, which plays the role of detoxification, benefiting qi and nourishing blood. If liver cancer occurs, especially if cancer cells invade the liver in the later stage, some symptoms will appear. Basically, early liver cancer may have no obvious symptoms, and many patients may think it is indigestion, abdominal distension, nausea and vomiting. However, if this situation is not taken seriously in the latter two periods, coupled with long-term drinking, fatty liver and viral hepatitis, it will appear under the stimulation of alcohol drugs.
Therefore, once the liver is found, most of them are symptoms in the middle and late stages, so we should start with early liver cancer and start with the following causes of liver cancer to treat the primary disease, especially early liver cancer.
Early liver cancer is a relatively small cancer cell in the liver. In this case, it is generally less than 3cm. Some people may be single or multiple, and there are many possibilities. In this case, it is necessary to review the liver indexes in time, especially the liver function of alpha-fetoprotein. Treat primary disease
The etiology of early liver cancer is mostly related to hepatitis, alcoholism and fatty liver, which may be caused by drugs.
The most common symptoms of liver cancer may have no obvious symptoms in the early stage, so it is difficult for many patients to find out the cause. Some people may have hepatitis, cirrhosis and liver fibrosis, which has not been paid attention to. In addition, long-term staying up late, fatigue, bad drinking and smoking will cause further damage to liver cells.
Abdominal distension, diarrhea, indigestion, nausea and vomiting may occur in the middle and late stage of liver cancer. In severe cases, there will be a lot of ascites, edema of both lower limbs, obstruction of superior vena cava, emaciation, fever and infection, and even malignant lesions on weekends.
Early treatment or surgical treatment of liver cancer, especially resection of the primary focus, has no metastasis after regular review.
After the operation, you should stay in bed absolutely, and check the liver regularly to see if there is metastasis.
The diet is convenient and rich in protein and cellulose.
Hello, I'm an oncologist, mother orange. I don't agree with the question raised by the subject, mainly depending on the staging of liver cancer. For example, the 5-year survival rate of small liver cancer after surgical resection can reach 90%, which means that 90% people can survive for at least 5 years after treatment. You say, is this an incurable disease? Obviously not. I'll talk to you about this problem from four aspects. 1. What are the clinical manifestations of liver cancer?
2. How to treat liver cancer?
3. What factors are related to the occurrence of liver cancer?
4. How to detect liver cancer early?
What are the clinical manifestations of liver cancer? Liver cancer refers to primary liver cancer. Because the incidence of liver cancer is hidden, early liver cancer has no typical symptoms and is not specific enough, and it is easy to be ignored or mistaken for gastroenteritis, such as fullness in the upper abdomen after meals, indigestion, nausea, vomiting, diarrhea and other symptoms. Is it easy to be confused with gastroenteritis? Advanced liver cancer usually has obvious clinical symptoms.
Learn how to treat liver cancer. What factors are related to the occurrence of liver cancer? How to find liver cancer by early screening? After reading the above, I think everyone has a general understanding of liver cancer. I would like to remind you that although there are no obvious symptoms in the early stage of liver cancer, it can be screened out by alpha-fetoprotein combined with liver color Doppler ultrasound. Early detection and early treatment have a significantly higher cure rate. If symptoms have appeared, it may be in the middle or late stage, or even in the middle or late stage, which by no means means means that there is no cure. It is suggested that you actively cooperate with the doctor for treatment, so as to improve the quality of life and prolong the survival time.
Found that liver cancer is not necessarily an incurable disease!
I have a friend here in Yulin City, Shanxi Province, a 9 cm liver cancer tumor. At that time, the hospital was unable to perform surgery, chemotherapy and radiotherapy, and did not receive treatment! He found a Chinese medicine practitioner and took Chinese medicine for about four months. The tumor completely disappeared. It has been three years now, and there is no recurrence. I opened a supermarket myself and lived a normal life. I asked him how he is now the other day. He said no problem. I can eat, walk and work, and there is nothing wrong with me! Do you think this Chinese medicine treatment of cancer is magical? There are therapeutic films, and some people are alive and well. Do not believe you can find the patient with liver cancer and ask, I will give you the address and contact information! I still have his list here. It's not that there is no cure, it's that I don't know how to cure it, and I don't know who to treat it!
The problem is too heavy. I'm not a professional doctor, so I won't say much and I don't have a picture. I just want to express my opinion.
1. Many people think they are young and don't pay attention to their health. When housekeepers feel unwell, they will give a signal in advance. Many people think that youth is capital, and a little problem doesn't matter, which leads to the failure to nip the disease in the bud in advance.
2. When there is something wrong with the self-examination report, I feel depressed and can't take the initiative to deal with the unexpected situation, which leads to the deterioration of my condition.
That's all!