It is about 540 kilometers from Wuhan to Zhengzhou. The speed from Wuhan Xiao Li to Zhengzhou is 1 10 km, and the speed from Zhengzhou Xiao Wang to Wuhan is 80 km/h.

2 hours, Xiao Li's trip 1 10× 2 = 220km.

Xiao Wang traveled 80×2= 160 km in 2 hours.

Two people * * * did 220+ 160=380 km.

Two hours later, they are still 540-380= 160 km apart.

Comprehensive formula

540-( 1 10+80)×2

=540-( 190)×2

=540-380

=160km