Genome field:
Genome is the cornerstone of genetic evolution. By analyzing the structural sequence information of DNA, we can study the genetic evolution relationship between species, develop molecular markers, correlate important traits and accurately locate genes related to diseases and important agronomic traits, which will provide favorable research tools for human health and agricultural production. Baimaike provides the following genome service products: whole genome sequencing, whole genome resequencing and whole exon sequencing.
Simplify the genome:
Slaf-Seq (Specific-Locus Amplified Fragment Sequencing) technology independently developed by Baimaike is a set of simplified genome sequencing technology. The latest version of SLAF2 technology represents a revolution in simplified genome sequencing with its long effective reading, Qualcomm capacity and flexible scheme design. It brings an effective genome reading length of 2 x 100 bp, provides an unprecedented customized service for enzyme digestion scheme, develops as many as 65,438+million tags at one time, and obtains the most complete genome variation images (SNPs, InDels), allowing researchers to select the most informative and reliable polymorphic markers, thus realizing the excellent ability of functional gene mapping of important agronomic traits.
RNA domain:
Transcriptomics is a discipline that studies gene transcription and transcription regulation in cells at the overall level. Studying gene expression at RNA level is an important means to study cell phenotype and function. Unlike genome, the definition of transcriptome contains time and space constraints. The gene expression of the same cell is not exactly the same in different growth periods and growth environments. Using the second generation high-throughput sequencing technology to sequence cDNA, almost all transcripts of a specific organ or tissue of a species in a certain state can be obtained comprehensively and quickly. Transcription sequencing can not only provide more accurate digital signals, higher detection flux and wider detection range, but also provide an accurate and efficient screening method for studying the relationship between miRNA and its corresponding target genes with the help of biological information.
Epigenetic domain:
Epigenetics refers to the heritable change of gene expression without changing DNA sequence. This change is the change of other heritable substances except genetic information in cells, which can be stably transmitted during development and cell proliferation, mainly including histone modification and DNA methylation. Combined with the most advanced high-throughput sequencing method, the related epigenetic variation was studied in the whole genome. The epigenetic solutions that Baimaike Biotechnology can provide you include chromatin immunoprecipitation sequencing (ChIP-seq), genome-wide methylation sequencing (WGBS) and reductive methylation sequencing (RRBS).
Microbiological field:
Microorganisms are widely distributed in various environments, with a long history of evolution and various types, and play an important role in the fields of environment, medicine, health, industry and so on. The development of technology in high-throughput sequencing provides a revolutionary research method for microbiology. Relying on the most advanced Illumina Hiseq 2500 sequencing platform and powerful computing hardware platform, Baimaike is equipped with a professional and experienced analysis team to provide customers in the field of microbiology with complete solutions from microbial genome sequencing to metagenome and environmental microbial diversity analysis. Biological cloud platform:
Baimaike Biological Cloud Service is a biological sequence data analysis and processing system independently developed by Baimaike based on a powerful data analysis platform for users to use remotely and online. Baimaike Biological Cloud Service provides comprehensive data analysis services integrating data processing, software analysis and computing resources. Users can submit data analysis requirements online, participate in parameter setting independently, and the analysis results can be presented in time.
The omics cloud platform is a cloud platform for scientific research users to manage and mine "biological big data" in the fields of genome and transcriptome. Professional software system, powerful computing power and good usability meet the all-round needs of researchers for omics research.
The medical cloud platform is a cloud platform for professional medical personnel. Through the management and analysis of personal genetic testing data, it provides personalized health data management services and diagnosis decision support such as disease prediction, disease diagnosis and personalized medication.
Breeding cloud platform is a professional cloud platform for molecular breeding, which systematically manages the massive phenotypic data and genotypic data generated in the process of molecular breeding, provides professional software systems and high-performance computing services, quickly obtains target varieties and improves the efficiency of molecular breeding.
Special server system for bioinformatics;
With the deepening of molecular biology research, scientists have ushered in the era of biological big data: hundreds of Gb of high-throughput sequencing data, huge biological sequence data, and complex protein structure data ... Biological big data brings a lot of information, but also brings various challenges:
1. The amount of biological data is huge, and the personal computer configuration is general, so it can't handle the analysis.
2. There are a large number of bioanalysis software, and it is complicated to download, install and set parameters.
3. The biological database is huge, and it is troublesome to download and debug.
4. The hardware compatibility of the purchased server is poor, and it is extremely difficult to use and maintain.
Through careful research and development, Baimaike Biotechnology perfectly integrated the software and database related to bioinformatics analysis into the well-equipped server hardware, and launched a powerful special server system for bioinformatics analysis.
Sequencing data analysis service:
For users who have some sequencing data in their hands and need a comprehensive reanalysis of the data, Baimaike also provides sequencing data analysis services. Professional data analysis talents and efficient analysis process ensure the fast and accurate sequencing data analysis service.