1, industry overview
Phospholipids are the basic components of human cells (cell membrane, nuclear membrane and plastid membrane), which are closely related to the functions of nerves, reproduction and hormones, and have high nutritional and medicinal values. Modern people's life rhythm is tense, and phospholipid nutrition is greatly lost, so it is absolutely necessary for modern people to supplement complete phospholipids (PC, PE, PI…). In view of the fact that soybean phospholipid health care product is a functional health food, although it has no immediate effect, it has a comprehensive, long-term and stable effect, and there is no side effect of drugs. Physicians have also begun to pay attention to the positive role of lecithin in preventing diseases.
Soybean phospholipid is a good natural surfactant and nutrient extracted from oil residue produced by soybean oil. It has many functional characteristics such as emulsification, softening, wetting, dispersion, infiltration, humidification, non-toxic, non-irritating, pollution-free, anti-oxidation and so on. It is a lipid compound with important physiological functions. In the medical field, phospholipids, as the basic substance of life, can be used as active ingredients to treat various diseases, as regulators and emulsifiers to prepare various pharmaceutical preparations, and can also be used to regulate the membrane function of the body, promote nerve conduction, promote fat metabolism, prevent liver dysfunction, improve blood circulation, enhance hematopoietic function, and prevent arteriosclerosis and cerebral hemorrhage.
Related report: Report on Market Segmentation Survey and Prospect Forecast of Soybean Phospholipid Industry in 2020-2026 by Beijing Puhua Youce Information Consulting Co., Ltd.
According to the different content of phosphatidylcholine, soybean lecithin, a pharmaceutical auxiliary material, can be divided into products with different phosphatidylcholine content, such as PC50-PC90. The higher the PC content, the higher the product level and the more difficult the technical operation. Phospholipids with high phosphatidylcholine content are beneficial to the formation of O/W emulsion, which is the key basic data for the preparation of pure natural emulsifiers and liposomes in pharmaceutical industry. At present, the biggest use of high PC content phospholipids in pharmaceutical industry is to prepare high-energy parenteral fluid-fat emulsion and carriers of various anticancer drugs.
2. From the perspective of competition pattern.
At present, the competition pattern of pharmaceutical auxiliary phospholipid production enterprises in the domestic market is obvious. Multinational enterprises with strong technical strength, financial strength and brand influence occupy market share in a large scale with high-tech content in the supply of high-purity PC phospholipid products, and few domestic enterprises can compete with them. At present, multinational companies mainly expand their influence and seize the market by setting up R&D and production bases in China. Domestic enterprises have also actively invested in the accumulation of talents and technology through years of production and operation practice, and strived to narrow the gap with multinational enterprises in the technical level of high-purity PC phospholipids.
China's pharmaceutical auxiliary phospholipid production enterprises have reached a certain scale, mainly including Shanghai Taiwei Pharmaceutical Co., Ltd., Jiangsu Man Biotechnology Co., Ltd., Shanghai Ai Kang Fine Chemical Co., Ltd. and Shenyang Tianfeng Biopharmaceutical Co., Ltd.. The basic situation of each competitor is as follows:
(1) Shanghai Taiwei Pharmaceutical Co., Ltd. is a new private high-tech company. The company's main products include soybean phospholipids for injection, soybean phospholipids for high-purity fat emulsion, egg yolk phospholipids for injection and other products. The company has workshops meeting GMP standards: 1 10,000 and 1 10,000 purification workshops, and has built equipment with an annual output of 10 ton of soybean phospholipids for injection.
(2) Shanghai Ai Kang Fine Chemical Co., Ltd. is an enterprise that mainly produces pharmaceutical excipients and fine chemical products. The company is a professional phosphatide manufacturer, and its main products include soybean phosphatide and lecithin (egg yolk phosphatide) for both medicine and food. At present, it has a GMP workshop of 500 square meters, an auxiliary production workshop of 2000 square meters, an R&D center of 1200 square meters and a warehouse of 1500 square meters, as well as a cold storage room, a boiler room, a power distribution room, special testing facilities and experimental facilities for production.
(3) Jiangsu Man Biotechnology Co., Ltd., which is mainly engaged in the research, development, production and sales of soybean phospholipids as pharmaceutical excipients. Products are mainly divided into three categories: oral, injection and powdered phospholipids. According to the use, the company's soybean phospholipid products are mainly divided into three categories: oral grade, injection grade and powdered phospholipid.
(4) Shenyang Tianfeng Bio-pharmaceutical Co., Ltd. is a high-tech pharmaceutical manufacturer integrating the extraction of plant raw materials, the production and sales of raw materials and preparations, and the research and development of anti-tumor high-tech products. The company takes paclitaxel (API), an anti-tumor drug supported by the state, as the main business project, and the leading natural plant extraction technology (industrial chromatography preparation technology) at home and abroad as the innovative means and breakthrough point, and invests in the planting, research and development and production of paclitaxel series anti-tumor new drugs and APIs in the Taxus project. At the same time, the company also supplies medicinal soybean phospholipid products.
3. From the upstream and downstream industrial chain.
From the industrial chain of pharmaceutical excipients-soybean phospholipids industry, the upstream suppliers are mainly concentrated phospholipids, acetone, alcohol and other raw materials suppliers, the middle reaches are pharmaceutical excipients-soybean phospholipids manufacturers, and the downstream markets are mainly pharmaceutical manufacturers, followed by some food reprocessing and cosmetics enterprises.
From the choice of suppliers in the upstream industry, concentrated phospholipids are one of the basic and important raw materials in the upstream industry. Concentrated phospholipids with high purity and few impurities are still mainly from foreign suppliers. Domestic concentrated phospholipid suppliers have also continuously strengthened the accumulation of talents and technology, narrowed the gap with foreign suppliers in product technology level, and strived to realize the localization of suppliers.
The downstream market demand is extensive, mainly in the pharmaceutical preparation industry. In the pharmaceutical industry, soybean phospholipids are known as "the protector of cells", "the scavenger of blood vessels", "the power to open the brain" and "edible cosmetics". It is an indispensable nutrient to ensure the normal metabolism of human body, and is often used to make drugs for treating cardiovascular diseases, fatty liver, gallstones and hypertension, as well as drugs for adjuvant treatment of neurasthenia and arteriosclerosis. Driven by the global economic and social development, medical and health undertakings will continue to progress and grow with the survival and development of human beings, and the total market demand for medicinal soybean phospholipids in pharmaceutical preparation industry will continue to grow, and the requirements for industrial upgrading and product innovation of medicinal soybean phospholipids will be further improved. With the gradual expansion of the market scale of the pharmaceutical industry, it has a great traction and pulling effect on the development of this industry.
4. From the technical level of the industry.
The study of soybean phospholipids began in Germany in 1930s and was industrialized in developed countries in 1960s. From the late 1970s to the early 1980s, phospholipid research was the most active period in the world. At present, the research on phospholipids has penetrated into various fields, and the main research contents include: separation and purification methods of phospholipids, nutritional functions of phospholipids, biological activities of phospholipids, uses of phospholipids, modification methods of phospholipids, etc. Purification and separation of phospholipids is one of the hot spots in industry at present.
The separation and purification of phospholipids have been studied a lot at home and abroad. The main methods for preparing soybean phospholipids include high performance liquid chromatography, column chromatography, solvent extraction, phospholipid derivation, ultrafiltration and so on. High performance liquid chromatography (HPLC) and column chromatography (LC) use adsorbents as stationary phases. Solutes in the mobile phase can be separated because they have different adsorption and desorption abilities. They are potential methods to prepare phospholipid products with high PC content, and the PC with a mass fraction of about 90% can be obtained, but the yield is very limited. Moreover, the research of this method mostly stays in the analysis and preparation, and gradient elution is required no matter which adsorbent is selected in the preparation process, which makes the solvent recovery very difficult.
Solvent extraction is a traditional method to separate soybean phosphatidylcholine by using different solubility of different phospholipid monomers in different solvents. It has the advantages of large production capacity, short cycle, convenient continuous operation, easy automation, relatively cheap solvent and easy recovery. However, due to the inability to control the phospholipid content other than PC and a small amount of non-phospholipid impurities, the yield is relatively low when preparing products above PC60.
Phospholipid derivatization method is mainly to derivatize mixed phospholipids, and use the difference and acetylation reaction to change the physical and chemical properties of soybean phosphatidylethanolamine and soybean phosphatidylcholine, so as to achieve the purpose of purifying soybean phosphatidylcholine. The main problem of this method is that acetylated phosphatidylethanolamine remains in the product and cannot be completely removed.
Ultrafiltration method is to select a semi-permeable membrane with a certain aperture, press the crude phospholipid solution dissolved by solvent through the semi-permeable membrane, and use the difficulties of phospholipid components with different molecular weights to achieve the separation effect. Membrane separation method has the advantages of low energy consumption, simple equipment, convenient operation and no new pollution. The separation process is usually carried out at room temperature, which is especially suitable for the separation of natural substances, but the membrane is not easy to regenerate, has poor repeatability and is expensive, so it is difficult to be applied in industry.
At present, domestic and foreign enterprises mostly use solvent extraction, column chromatography and other methods to produce pharmaceutical high PC soybean phospholipids on a large scale. Extracting "deoiled phospholipids" with ethanol, using concentrated phospholipids as raw materials, using anhydrous ethanol and acetone as solvents respectively, enriching phosphatidylcholine and removing grease from phosphatidylcholine, and preparing high-purity phosphatidylcholine soybean phospholipids products.
In recent years, China's pharmaceutical excipients industry has developed rapidly as a new industry, and soybean phospholipids, as one of pharmaceutical excipients, have also made great progress, which has promoted the research and development and production of high-purity PC phospholipids in the industry. With domestic enterprises gradually investing in the research and development and production of high-end pharmaceutical phospholipid products, the monopoly of multinational enterprises is being gradually broken.
5. Industry risks
(1) scientific and technological R&D risk
The production of pharmaceutical auxiliary phospholipid products is a technology-intensive industry, and advanced production technology determines whether the corresponding products can be successfully developed and competitive in the market. At present, domestic enterprises have invested a lot of R&D efforts in the production technology of pharmaceutical excipients phospholipids, and strive to catch up with the technical level of multinational enterprises. However, because the R&D and production of pharmaceutical auxiliary phospholipid products involve repeated extraction, drying and concentration of raw materials such as oil residue and concentrated phospholipid, its technical process is exquisite and complicated, and it is difficult to realize the development and production of high-purity PC phospholipid products without long-term technology and experience accumulation. Domestic soybean phosphatide manufacturers need to strengthen the accumulation of talents and technology and form a strong ability to independently develop new products if they want to compete with leading enterprises at home and abroad and maintain their own technological advancement. Once enterprise technology loses its technological advancement, it will bring adverse effects to the long-term development of enterprises.
(2) the risk of multinational enterprises participating in the competition
Due to the early development of multinational soybean phospholipid manufacturers with strong technical strength, financial strength and brand influence, such as Li Baoyi, Germany, they occupy market share in the supply of high-purity PC phospholipid products with obvious advantages such as product quality and high technical content, and few domestic enterprises can compete with them. At present, multinational companies mainly expand their influence and seize the market by setting up R&D and production bases in China. Domestic enterprises need to continuously explore the market, expand the industrial scale, actively invest in the accumulation of talents and technology, improve the R&D and production capacity of high-purity PC phospholipids, and improve their ability to compete with multinational companies in the high-end phospholipid market. At present, the development of soybean phospholipid production enterprises in China will still face the pattern of competition with multinational enterprises.
catalogue
The first chapter summarizes the soybean phospholipid market.
Section 1 Overview of Soybean Phospholipids Market
First, the definition of soybean phospholipid products
Second, the classification of soybean phospholipid products
Section 2 Life Cycle Analysis of Soybean Phospholipid Industry
The second chapter 20 15-20 19 global soybean phospholipid market analysis.
The first quarter 20 15-20 19 Analysis of the current situation of the international soybean phospholipid market
First, the development process of the international soybean phospholipid market
Second, the development analysis of soybean phospholipids in major international countries
Third, the development trend of the international soybean phospholipid market
Section 2 Analysis on the Development Environment of Soybean Phospholipids
First, the analysis of China's macroeconomic environment.
Second, the European economic environment analysis
Third, the analysis of American economic environment.
Fourth, Japan's economic environment analysis
Verb (abbreviation of verb) Analysis of economic environment in other regions
An analysis of the global economic environment of intransitive verbs
The third quarter 20 15-20 19 China soybean phospholipid market analysis.
Statistical analysis on the market size of soybean phospholipids in China in1.2015-2019 years.
2.20 15-20 19 years' statistical analysis of soybean phospholipids market supply in China.
Three. Statistical Analysis of Soybean Phospholipids Market Demand in China in 20 15-20 19 Years
Four. Statistical analysis of soybean phosphatide industry capacity in China in 20 15-20 19 years.
1, 20 15-20 19 China soybean phosphatide industry capacity statistics.
2. 20 15-20 19 Analysis of the capacity allocation and capacity utilization rate of soybean phosphatide industry in China.
V. Analysis of pests (environment) in soybean phosphatide industry in China on 20 15-20 19.
1, economic environment analysis
2. Policy environment analysis
3. Social environment analysis
4, technical environment analysis
Chapter III 20 15-20 19 Investigation and Analysis on the Supply and Demand Balance of Soybean Phospholipids Market in China.
The first quarter 20 15-20 19 analysis of supply and demand balance of soybean phospholipids market in China.
20 15-20 19 Analysis on the Influencing Factors of Supply and Demand Balance in Soybean Phospholipids Market in the Second Quarter
Section III Analysis and Forecast of Supply and Demand Balance Trend of Soybean Phospholipids Market in 2020-2026
The fourth chapter analyzes the market price trend of soybean phospholipids and its influencing factors.
The first quarter 20 15-20 19 China soybean phospholipid product price statistical analysis.
Section II Current Market Price of Soybean Phospholipid Products in China
First, the current price analysis of soybean phospholipid products
Second, the main production enterprises soybean phospholipid product price survey
Section III Analysis of Influencing Factors of Soybean Phospholipid Industry Product Price in China.
The fifth chapter is the analysis of the development characteristics of soybean phospholipid market.
Section 1: Periodic and Seasonal Characteristics of Soybean Phospholipids Market
In the second quarter, soybean phospholipid market barriers
First, the technical barriers of soybean phospholipid market
Second, the soybean phospholipid market capital barriers
Third, other barriers in the soybean phospholipid market.
The third quarter SWOT analysis of soybean phospholipid market development
First, analysis of the development advantages of soybean phospholipids market
Second, the development disadvantage analysis of soybean phospholipid market
Third, the market opportunity analysis of soybean phospholipids
Fourth, the threat analysis of soybean phospholipid market
Section IV Analysis of Competition Degree of Soybean Phospholipids Market
First, the market concentration analysis
Second, the type of market competition analysis
Third, the competitive strategy analysis of key enterprises
Chapter 6: Operation analysis of key areas of China soybean phospholipid market in 20 15-20 19.
Section 1 East China Market Operation from 20 15 to 20 19
I. Market size in East China
Second, the characteristics of the East China market
Third, the analysis of East China market potential
Section 2 20 15-20 19 South China Market Operation
I. Market size of South China
Second, the characteristics of the South China market
3. South China market potential analysis
The third quarter 20 15-20 19 Central China Market Operation
First, the size of the Central China market
Second, the characteristics of the Central China market
3. Central China market potential analysis
Section 4 20 15-20 19 North China Market Operation
I. Market size in North China
Second, the characteristics of the North China market
Third, North China market potential analysis
Section 5 Northwest Market Operation from 20 15 to 20 19
I. Market Size in Northwest China
Second, the characteristics of the northwest market
Third, the analysis of market potential in Northwest China
Section 6 Southwest Market Operation from 20 15 to 20 19
First, the size of the southwest market
Second, the characteristics of the southwest market
Third, the analysis of market potential in Southwest China
Section 7 Operation of Northeast Market from 20 15 to 20 19
First, the size of the Northeast market
Second, the characteristics of the Northeast market
Third, the Northeast market potential analysis
Chapter VII Market Analysis of Soybean Phospholipid Subdivision Products
Section 1 Subdivision Structure of Soybean Phospholipid Products
In the second quarter, the demand analysis of soybean phospholipid products in each sub-product (demand characteristics and demand proportion).
The third section forecasts the market prospect of key segments of soybean phospholipid products from 2020 to 2026.
Chapter VIII Analysis of Import and Export Data of China
Section 1 Import Analysis
I. Statistical Analysis on the Import and Growth Rate of Soybean Phospholipid Products in Recent Three Years
Two. Statistical analysis of import and growth rate of soybean phospholipid products in recent three years
Three. Statistical analysis of import price of soybean phospholipid products in recent three years
Fourth, the product structure analysis of imported soybean phospholipids
Five, analysis of factors affecting the import of soybean phospholipid products
Analysis and forecast of import situation of soybean phospholipid industry in 2020-2026
Section 2 Export Analysis
1. Statistical analysis of export volume and growth rate of soybean phospholipid products in recent three years
The second is the statistical analysis of the export volume and growth rate of soybean phospholipid products in recent three years.
Third, statistical analysis of export prices of soybean phospholipid products in recent three years
Four. Sales of export products in overseas markets
Five, analysis of factors affecting the export of soybean phospholipid products
Analysis and forecast of export situation of soybean phospholipid industry in 2020-2026
Section III Import and Export Policies of Soybean Phospholipid Products
Chapter IX Analysis of Major Production Enterprises of Products
Section 1 company a
First, the basic situation of enterprise development
Second, the enterprise main product analysis
Third, analysis of soybean phospholipid production and marketing data
Fourthly, the analysis of the operating conditions of enterprises.
Five, enterprise product production layout
Six, enterprise sales network layout
Seven, enterprise development strategy analysis
Section 2 Company B
First, the basic situation of enterprise development
Second, the enterprise main product analysis
Third, analysis of soybean phospholipid production and marketing data
Fourthly, the analysis of the operating conditions of enterprises.
Five, enterprise product production layout
Six, enterprise sales network layout
Seven, enterprise development strategy analysis
Section 3 company c
First, the basic situation of enterprise development
Second, the enterprise main product analysis
Third, analysis of soybean phospholipid production and marketing data
Fourthly, the analysis of the operating conditions of enterprises.
Five, enterprise product production layout
Six, enterprise sales network layout
Seven, enterprise development strategy analysis
Section 4 Company D
First, the basic situation of enterprise development
Second, the enterprise main product analysis
Third, analysis of soybean phospholipid production and marketing data
Fourthly, the analysis of the operating conditions of enterprises.
Five, enterprise product production layout
Six, enterprise sales network layout
Seven, enterprise development strategy analysis
Section 5 Company E
First, the basic situation of enterprise development
Second, the enterprise main product analysis
Third, analysis of soybean phospholipid production and marketing data
Fourthly, the analysis of the operating conditions of enterprises.
Five, enterprise product production layout
Six, enterprise sales network layout
Seven, enterprise development strategy analysis
Chapter 10 Competition Pattern of Soybean Phospholipids Market in China and Evaluation of Enterprise Competitiveness 20 15-20 19
Section 1 Theoretical Basis of Competitiveness Analysis of Similar Products
Section 2 Number of Domestic Enterprises and Brands of Similar Products
Section 3 Analysis of Competition Pattern of Similar Products
The fourth quarter similar product competition group analysis
Section 5 Evaluation of Market Competitiveness of Major Enterprises
Chapter III Analysis of XI Industry Channels and Consumers
Section 1 Analysis of Marketing Channels of Soybean Phospholipids Industry
I. Traditional channels
Second, the network channel.
Third, the influence of various channels on soybean phospholipid industry
Four, the main soybean phospholipid enterprise channel strategy research
Section 2 Analysis of Major Customer Groups in Soybean Phospholipid Industry
First, the characteristics of customer demand
Second, the customer base structure.
Third, the demand trend of customer base.
Chapter XII Analysis and Research of Upstream and Downstream Supply Chain
The first quarter 20 15-20 19 upstream raw material price analysis of soybean phospholipid industry
The second quarter 20 15-20 19 downstream application analysis of soybean phospholipids industry
Section III Analysis of Major Suppliers of Soybean Phospholipid Raw Materials
Section IV Analysis of Major Customers of Soybean Phospholipids Downstream
Chapter XIII Analysis of Complementary Products of Market Substitutes
Section 1 Analysis of Product Substitutes
I. Development Status of Substitutes
Second, the influence of substitutes on soybean phospholipid industry
Third, the development trend of substitutes
Section 2 Product Complementary Product Analysis
First, the development status of complementary products
Second, the impact of supplementary products on soybean phospholipid industry
Third, the development trend of complementary products
Chapter XIV Analysis and Forecast of Soybean Phospholipids Market Development from 2020 to 2026
The first section is the market scale forecast of soybean phospholipids in China from 2020 to 2026.
In the second quarter, 2020-2026 China soybean phosphatide industry capacity forecast.
In the third quarter, the supply forecast of soybean phosphatide products in China from 2020 to 2026.
The fourth quarter 2020-2026 China soybean phosphatide product price forecast.
Section V Market Demand Forecast of Soybean Phospholipids in China from 2020 to 2026
Chapter 15 Market Risk Tips of Soybean Phospholipids
Section 1 Environmental Risk of Soybean Phospholipid Market
Section 2 Policy Risks of Soybean Phospholipid Industry
Section 3 Market Demand Risk of Soybean Phospholipids
Chapter XVI Investment Opportunities and Investment Strategy Suggestions in 2020-2026
Section 1 Investment Opportunities
I. Investment opportunities in sub-sectors
Second, regional market investment opportunities
Third, industrial chain investment opportunities
Section 2 Suggestions on Investment Strategy
I. Product Positioning and Pricing
Second, cost control.
Third, technological innovation.
Fourth, channel construction and marketing strategy