Drug consultation for treat cerebral vasodilation

What are the commonly used vasodilators?

(1) Papaverine hydrochloride can relax smooth muscle, especially directly dilate cerebral vessels. It can also reduce peripheral vascular resistance and cerebrovascular resistance, increase cerebral blood flow and improve cerebral oxygen supply. The usual dosage is 30 ~ 60mg, taken orally three times a day, or 60 ~ 90mg and 500ml of 5% glucose, once a day, 7 ~ 1 0 days as a course of treatment.

(2) cyclandelate (Kangshuan Pill) is similar to papaverine, which can relax vascular smooth muscle, dilate blood vessels in brain, kidney, coronary artery and limbs, increase blood flow and improve microcirculation. Its effect is mild and lasting. The usual dosage is 100 ~ 200mg, taken orally three times a day.

(3) Nicotinic acid can dilate cerebral vessels, increase blood flow, promote nerve cell metabolism and lower cholesterol. The usual dosage is 50 ~ 100 mg, 1, three times a day, or 200 ~ 300 mg plus 500 ml of 5% glucose, once a day, 7 ~ 1 0 days.

(4) Calcium channel blockers, such as Naoyizine, Flunarizine and Nimodipine. It can act on calcium channels on cell membrane, prevent calcium ions from entering cells, relieve vasospasm and dilate blood vessels. It can selectively act on cerebral vessels, increase cerebral blood flow and improve cerebral microcirculation. Dosage: Naoyizine 25 ~ 50mg, taken orally three times a day; Flunarizine 8 ~ 12 mg, taken every night 1 time; Nimodipine 20 ~ 40 mg, three times a day, orally.

(5) Betadine has a strong effect on dilating cerebral vessels, improving cerebral blood circulation and increasing cerebral blood flow. In particular, it has a strong dilating effect on the vertebrobasilar artery system. Usually the dosage is 4 ~ 8 mg, taken orally three times a day.

(6) Sodium bicarbonate can increase the concentration of carbon dioxide in blood, cause metabolic alkalemia, dilate blood vessels, increase cerebral blood flow and improve cerebral ischemia. The usual dosage is 250 ml intravenous drip of 5% sodium bicarbonate,/kloc-0 once a day, and/kloc-0 once every 7 ~/0 days.

(7) Kalan tablet can relax vascular smooth muscle, increase cerebral blood flow, reduce blood viscosity and inhibit platelet aggregation. The usual dose is 5 mg, taken orally three times a day.

(8) Weinaolutong can inhibit platelet and erythrocyte aggregation, reduce capillary permeability and brittleness, and improve cerebral circulation. The usual dosage is 200 ~ 300mg, taken orally three times a day, or 400 ~ 600mg plus 500ml of 5 ~ 1 0% glucose intravenously, once a day, 10 ~ 15 days as a course of treatment.

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