I should be very happy, because after a long voyage, being able to see land means that he has basically completed the first step of his task (finding land), and the second step is to discover wealth.
According to Columbus' account, when he and his crew arrived at those houses, why was there no one?
Because the local residents are still in the primitive society, one reason is that the local people really have never seen outsiders, so they run away in fear. Another reason is that the local people need to go out to get food, so Columbus arrived just when they all left their homes.