1. Laboratory test: The concentration or activity of growth factor can be determined by laboratory test. This includes quantitative determination of growth factors by enzyme-linked immunosorbent assay (ELISA) and radioimmunoassay (RIA). By comparing the experimental results with normal reference values or control groups, the level of growth factors can be determined.
2. Clinical symptoms and signs: Abnormal increase or decrease of some growth factors will lead to specific clinical symptoms and signs. For example, too much growth hormone in the anterior pituitary gland may lead to gigantism or obesity, while lack of growth factors may lead to dwarfism. Observing the signs and symptoms of patients can provide some clues to judge the level of growth factors.
3. Imaging examination: Some growth factor abnormalities are related to tumors, such as epidermal growth factor receptor (EGFR) and some cancers. By using imaging examination (such as x-ray, CT scan, MRI, etc. ), we can observe the existence of tumor and the expression of growth factor receptor.
It should be noted that judging the level of growth factors requires comprehensive consideration of multiple factors, and different growth factors may have different judgment methods. Therefore, under specific circumstances, it is best to consult a doctor or a professional laboratory for accurate judgment and explanation.