Zhongsheng pharmaceutical freeze-dried powder injection workshop Is it hard? Has anyone done it there?

From the main process flow of freeze-dried powder injection workshop: ampoule or penicillin bottle with prepared liquid medicine → pre-freezing → sublimation drying → re-drying, the work is relatively loose and will not be too tired. But when working, we must be careful and complete the standards required by each working procedure.

Attachment: Detailed explanation of the main process flow of freeze-dried powder injection workshop.

Pre-freezing: Pre-freezing is a constant pressure cooling process.

Sublimation drying: the main process of freeze drying, the sublimation condition: 1, to ensure that the ice does not melt; 2. The water vapor pressure around the ice is lower than the saturated vapor pressure (there are two methods: one sublimation method and repeated freezing sublimation method).

Re-drying: after sublimation, there are many holes in the material, and the residual unfrozen water is still about 10% in the mechanism of single material. If the temperature continues to rise to 0℃ or room temperature for a period of time, the sublimated water vapor or residual water can be pumped out. After drying, the moisture content of freeze-dried products can be ensured to be less than 65438 0%, and the moisture regain can be prevented.