According to China's relevant laws and regulations, the legality of traditional Chinese medicine trading in Li Shizhen needs to be specifically analyzed. Under certain conditions, Chinese herbal medicines in trading agent are legal and can be agreed in the form of authorization contracts. However, the agency behavior needs to be carried out under legal qualifications. In the process of agency, it is necessary to abide by the relevant laws and regulations of Chinese herbal medicine trading to ensure the legitimacy and compliance of agency estoppel. Without permission, medicinal materials mixed with fake and shoddy materials shall not be sold, otherwise they will be punished by relevant administrative departments. In short, we should abide by relevant laws and regulations and avoid illegal acts.