Pharmacological and Toxicological Effects of Xinyue Capsule

The results of preclinical animal experiments show that intravenous injection of this product can regulate myocardial hemodynamics, reduce myocardial oxygen consumption, protect myocardial ischemia and reduce infarct area in dogs. Gastric administration can inhibit the increase of serum creatine phosphokinase, lactate dehydrogenase, lipid peroxide and free fatty acid in rats with myocardial ischemia. It can reduce the blood pressure of spontaneously hypertensive rats and prolong the survival time of mice injected with isoproterenol under normal pressure. Intraperitoneal injection can increase myocardial nutrient blood flow in mice.