Although the benefits of ibuprofen cover almost all the pain you experience in your daily life, people who take it should pay attention. Ibuprofen is not everything. If you use it in the wrong place, it will make your condition worse. There is no denying that ibuprofen has many advantages, but only by using ibuprofen reasonably and safely can the possibility of adverse reactions be reduced, the maximum curative effect of ibuprofen be exerted and health be protected. Let me give you a detailed introduction to the usage and precautions of ibuprofen:
1. What is ibuprofen?
Ibuprofen is a nonsteroidal anti-inflammatory drug, which is used for antipyretic, analgesic and anti-inflammatory. By inhibiting cyclooxygenase, the synthesis of prostaglandin is reduced, resulting in analgesic and anti-inflammatory effects; In addition, it can also play an antipyretic role by acting on the thermoregulatory center of hypothalamus (commonly known as "antipyretic"). Ibuprofen can relieve a variety of pains, and its efficacy covers almost all kinds of pains encountered in daily life. However, blindly taking painkillers may delay the illness.
Second, is ibuprofen really a universal painkiller? The answer is: no.
Ibuprofen can relieve a variety of pains, including headache, joint pain, migraine, toothache, muscle pain, neuralgia, dysmenorrhea, postoperative pain and low back pain. It can be seen that the efficacy of ibuprofen covers almost all kinds of pain encountered in daily life, but please note that if you encounter some pain, blindly taking painkillers may delay your illness, the most dangerous of which is the pain caused by heart disease, so you should seek medical attention as soon as possible.
Third, how to take ibuprofen correctly?
Choose to take medicine at meals or 30 minutes after meals, so that food can protect the intestines and avoid irritation to the gastrointestinal tract. And don't take other antipyretic and analgesic drugs at the same time to prevent the adverse reactions from getting worse, especially aspirin. Although aspirin and ibuprofen are both antipyretic and analgesic drugs, taking them together will increase the risk of coronary heart disease and myocardial infarction. Note that the interval between two doses should not be less than 4 hours.
We should also know that there are many kinds of ibuprofen. If children take it, choose drops or suspension liquid medicine, but remember to take it according to the weight of children under the guidance of a doctor, and don't overdo it.
At the same time, pay attention to the influence of ibuprofen on kidney and digestive system, and you can't take it for a long time. If the symptoms do not improve after 3~5 days of use, you should seek medical advice in time. And when taking drugs, you can't drink alcohol or drink alcoholic drinks. Because alcohol mixed with such drugs will lead to adverse reactions in the digestive tract, and in severe cases, it will lead to gastric bleeding.
Fourth, what circumstances can't use ibuprofen?
1, allergic reaction
Buprofen tablets are non-steroidal anti-inflammatory drugs with sedative and analgesic effects. Patients who are allergic to aspirin or other non-steroidal anti-inflammatory drugs should not take it. People who are allergic to such drugs should be vigilant. Once taken, it will produce a reaction and seriously endanger life. Or have allergies, consult a doctor before taking the medicine.
2. Poor heart and kidney function
Patients with poor heart function or severe heart failure should not take this medicine, because this kind of medicine will need to be excreted through the kidney, which will increase the burden on the kidney and inhibit the synthesis of prostaglandin, resulting in water and sodium staying in the body and not being excreted, thus increasing the incidence of nephropathy.
3. Pregnant women
The medicinal properties of ibuprofen will be directly absorbed by the fetus through the placenta, so pregnant women are forbidden to prevent the fetus from absorbing drugs and affecting its development.
Step 4 get pregnant
Most parturients need breastfeeding, and ibuprofen will be sucked by newborns through milk, thus making drugs harmful to newborns.
5, gastric ulcer or active bleeding.
Ibuprofen can irritate the gastrointestinal tract, and patients with gastric ulcer or active bleeding should not take it.
5. Is there any side effect when ibuprofen is eaten too much? Of course there is.
The following side effects may occur after taking ibuprofen normally:
Nausea, vomiting, heartburn, mild dyspepsia, headache, dizziness, tinnitus, blurred vision, mental stress, drowsiness, edema of lower limbs or sudden weight gain, etc.
If taken in excess or for a long time, it may cause serious side effects:
Including serious gastrointestinal reactions (such as bleeding, ulcer, perforation, manifested as hematemesis, melena, abdominal pain, abdominal distension and so on. ), serious cardiovascular thrombosis events (such as chest pain, shortness of breath, fatigue, slurred speech, etc. ), as well as serious skin reactions (such as exfoliative dermatitis, Shek Moon syndrome).
If we have the above symptoms during taking the medicine, or have a rash or other allergic reactions when taking the medicine for the first time, please stop taking the medicine and seek medical advice. Drugs are used to treat diseases. No matter what kind of medicine it is, it is three-point poison. Don't refuse to use ibuprofen, a classic and efficient drug, because of incomplete information. At the same time, you must read the drug instructions, follow the doctor's advice, use drugs rationally, and avoid side effects.
6. A senior three student in Ningbo was diagnosed with acute renal failure after taking four painkillers for three hours because of leg pain after exercise. Why can it cause acute renal failure?
Simply put, NSAIDs can inhibit cyclooxygenase and reduce prostaglandin synthesis; Renal prostaglandin is the main vasodilator of kidney, so it usually involves renal ischemic injury, which is manifested as acute renal injury. In addition, it will also lead to electrolyte and acid-base imbalance, acute interstitial nephritis complicated with nephrotic syndrome, and renal nipple necrosis.
When acute renal injury occurs, it is generally manifested as an increase in serum creatinine (this is one of the most commonly used indicators for monitoring renal function and requires blood test). Some severe patients may also have other manifestations, such as oliguria or anuria, edema and so on. Generally speaking, renal function can be restored after drug withdrawal. If renal function fails to recover within 3-7 days after drug withdrawal, renal biopsy is needed. Follow-up may require fluid replacement, hormone therapy, etc. Very few people may need dialysis.
If the intervention is timely, the renal function is expected to be completely relieved, but the treatment is delayed and the recovery situation can only vary from person to person. Therefore, try to find and intervene early! Drink plenty of water when taking painkillers, which can greatly reduce the risk of kidney damage! You must follow the doctor's advice when taking medicine, and you can't make your own decisions.