ISBN:78 1066983
Author: He Cheng
Press: China Agricultural University Press.
Pricing: 30 pounds
Page count: 337
Release date: March 2006-1
Version: 1
Format: 23cm
Packing: paperback
Introduction: This book covers the laws, regulations, policies and rules of experimental animals; Methods and standards for genetic naming and genetic testing of experimental animals; Varieties, feeding, facilities and management of experimental animals; Experimental animal models, disease and microbial detection standards; Basic requirements of animal experiment technology and animal experiment; Online learning materials related to experimental animals. The language strives to be easy to understand, informative and rich, and expands the thinking space. The purpose is to open a window for readers to understand the science of experimental animals, broaden their horizons, satisfy their thirst for knowledge, raise scientists' awareness of using qualified animals, advocate treating animals well, improve the welfare of experimental animals, and obtain scientific experimental conclusions. I hope this book can be used as a textbook for experimental animal science to contribute to scientists, graduate students and undergraduates who like experimental animals, and also as a training textbook for researchers engaged in animal experiments, professionals working in the field of experimental animals and veterinarians.
Directory:
The first chapter is introduction.
Section 1 Concepts of Experimental Animal Science
First, the definition of experimental animals
Second, the scientific research scope of experimental animals
Section 2 Past, Present and Future of Experimental Animals and Life Sciences
First, the role of experimental animals in promoting the development of life science in the past.
Second, the role of experimental animals in promoting modern biomedicine
Thirdly, the influence of experimental animals on the future development of life science.
Fourthly, life science supports the development of experimental animals.
Section III General Situation of the Development of Laboratory Animal Science
First, the development of foreign experimental animals
Second, the development of experimental animals in China
Application and development of animal substitution test in life science
First, the concept of humanization.
Second, the basic connotation of 3R
The Significance of the Third and 3R Research
Fourth, the research progress of animal substitution abroad
Verb (abbreviation of verb) Research Progress of 3R in China Experimental Animals
Chapter II Introduction of Domestic and Foreign Laboratory Animal Management Institutions and Regulations
Section 1 Management and Regulations of Foreign Laboratory Animals
I. international association for experimental animal science
II. European Regulation on Laboratory Animals
Iii. Regulations on Laboratory Animals in North America
Four, Australia's experimental animal laws and regulations
Verb (abbreviation of verb) Regulations on experimental animals in Asian countries
An analysis of foreign laws and regulations on intransitive verbs
Section II Management and Regulations of Laboratory Animals in China
I. National management regulations
Second, the local management regulations
Three, the characteristics of China experimental animal management laws and regulations system
Section III Training and Education of Experimental Animals in China
I. Legal basis
Second, the content of training and education
Third, implement training and education.
Chapter III Genetics and Quality Control of Experimental Animals
Section 1 Development History of Laboratory Animal Genetics
First, the classic era of genetic research.
Second, the development of molecular biology technology in the field of genetics
Section 2 Genetic Classification of Experimental Animals
First, the concept of experimental animal varieties and strains
Second, genetic classification.
Section 3 Characteristics and Application of Inbred Animals
I. Basic concepts
Second, the naming of inbred lines
Third, the characteristics and application of inbred animals
Four, special types of inbred lines and their applications
Five, breeding methods of inbred animals
Section 4 Characteristics and Application of Closed Group Animals
I. Basic concepts
Second, the classification of closed animals
Third, the naming of closed animals.
Fourth, the characteristics and application of closed animals
Five, closed group animal breeding methods
Section 5 Characteristics and Application of Hybrid Animals
I. Basic concepts
Second, naming
Third, the characteristics of mixed groups.
Fourthly, the application of hybrid animals in biomedicine.
Five, breeding methods of hybrid animals
Section 6 Genetic Quality Control of Experimental Animals
I. Purpose of genetic monitoring
Second, the main methods of genetic monitoring
Third, gene quality standards.
Chapter IV Commonly Used Experimental Animals
Section 1 Biological characteristics, selection, application and feeding management of mice
I. Biological characteristics
Second, the application of mice in biomedicine
Three, the main varieties and strains of mice
Fourthly, the management of rat breeding.
Section II Biological Characteristics, Selection, Application and Feeding Management of Rats
I. Biological characteristics of rats
Second, the main varieties and strains of rats
Third, the application of rats in biomedicine.
Four, rodent breeding and feeding management
Verb (abbreviation of verb) Feeding and management of rats
Section III Biological Characteristics, Selection, Application and Feeding Management of Guinea Pigs
I. Biological characteristics of guinea pigs
Second, the common varieties and strains of guinea pigs
Third, the application of guinea pigs in biomedicine.
Fourth, the management of guinea pig feeding
Section IV Biological Characteristics, Selection, Application and Feeding Management of Hamster
First, the biological characteristics of hamster
Second, the main species and strains of hamsters
Selection of hamster and its application in biomedicine
Fourth, hamster feeding management
Section 5 Biological Characteristics, Selection, Application and Feeding Management of Rabbits
First, the biological characteristics of rabbits
Second, the main varieties and strains of rabbits
Third, the selection and application of rabbits in biomedicine
Fourth, rabbit feeding management
Section VI Biological Characteristics, Selection, Application and Feeding Management of Dogs
First, the biological characteristics of dogs
Second, the main breeds and strains of dogs
Third, the selection and application of dogs in biomedicine
Four, dog feeding management
Section 7 Biological Characteristics, Selection, Application and Feeding Management of Cats
First, the biological characteristics of cats
Second, the main varieties and strains of cats
Third, the choice and application of cats in biomedicine
Fourth, the management of cat feeding
Section 8 Biological characteristics, selection, application and feeding management of nonhuman primates
I. Biological characteristics of nonhuman primates
Second, the main species and strains of nonhuman primates
Thirdly, the application of macaques in biomedicine.
Fourth, the management of macaque feeding
Section 9 Biological Characteristics, Selection, Application and Feeding Management of Chickens
First, the biological characteristics of chickens
Second, the main chicken breeds and strains
Third, the selection and application of chicken in biomedicine
Fourth, the management of chicken feeding
Section 10 Biological characteristics, selection, application and feeding management of miniature pigs
First, the biological characteristics of miniature pigs
Second, the main strains and populations of miniature pigs
Thirdly, the selection and application of miniature pigs in biomedicine.
Four, small pig feeding management
Section 11 Biological characteristics, selection, application and feeding management of experimental fish
First, the biological characteristics of experimental fish
Second, the main varieties and strains of experimental fish
Selection and application of experimental fish in biomedicine
Four, experimental fish feeding management
Chapter V Facilities and Equipment for Experimental Animals
Section 1 Classification of Laboratory Animal Facilities
First, the concept of experimental animal facilities
Second, the classification of experimental animal facilities
Section 2 Requirements for the Construction of Laboratory Animal Facilities
I. Site Selection
Second, the distribution and layout principles of the facilities area
Third, the layout of experimental animal facilities
Four, the construction requirements of experimental animal facilities
Section 3 National Standards for Experimental Animals and Animal Experimental Environment
I formulation of national standards
Second, the 200 1 version of the national standard
Section 4 Main Equipment of Animal Facilities
First, the air purification system equipment
Second, power supply, lighting and communication equipment
Third, the security and alarm system.
Fourth, disinfection and sterilization equipment
Five, microbial control equipment and feeding equipment
Section 5 Special experimental animal facilities for biological hazards
First, the classification of microbial hazards in infection experiments
Second, the biosafety laboratory facilities and use requirements
Three, the construction requirements of special animal experimental facilities
Section 6 Animal experimental facilities contaminated by radiation
I. Design of experimental facilities for radioactive contaminated animals
Two, radiation (radiation) pollution protection experimental facilities safety monitoring
Chapter VI Nutrition and Feed Quality Control of Experimental Animals
Section 1 Classification and Nutritional Characteristics of Feed for Experimental Animals
First, the classification of feed
Second, the nutritional characteristics of commonly used feed
Section II Nutritional Needs of Experimental Animals
First, the nutritional needs of mice.
Second, the nutritional needs of rats
Third, the nutritional needs of hamsters.
Fourthly, the nutritional needs of guinea pigs.
Five, the nutritional needs of rabbits
Sixth, the nutritional needs of dogs.
Seven, the nutritional needs of cats
Eight, the nutritional needs of non-human primate experimental animals
Section 3 Design of Compound Feed for Experimental Animals
I. Types of compound feed
Second, the design of feed formula
Section 4 Processing, Disinfection and Storage of Feed
First, the purchase of feed
Second, the custody of feed
Third, the processing and modulation of feed.
Fourth, the disinfection of feed.
Section 5 Nutritional monitoring of experimental animal feed
First, the purpose of nutrition monitoring
Second, feed nutrition monitoring methods
Third, the quality control of feed
Chapter VII Animal Models of Human Diseases
Section 1 Overview of Animal Models
First, the significance of animal models of human diseases
Second, the replication principle of animal models of human diseases
Thirdly, the classification of animal models of human diseases.
Fourthly, the factors that affect the quality of animal models.
Section 2 Replication of Common Animal Models
First, the tumor animal model
Second, animal models of digestive system diseases
Third, animal models of respiratory diseases
Four. Animal model of cardiovascular disease
Verb (abbreviation of verb) Animal model of endocrine and nutritional metabolic diseases
Six, animal models of infectious diseases
Seven, reproductive medicine animal model
Section III Animal Model of Immunodeficiency
I. classification of immunodeficient animals
Second, the characteristics and application of immunodeficient animals
The fourth quarter transgenic animal disease model
First, the naming of genetically modified animals
Second, transgenic animal disease model
Chapter VIII Common Diseases and Microbial Quality Control of Laboratory Animals
Section 1 Grades of Experimental Animals and Classification of Infectious Diseases
First, the classification of experimental animals
Second, the classification of infectious diseases in experimental animals
Section 2 Harm of Diseases in Laboratory Animals
First, the outbreak of infectious diseases directly caused huge losses.
Two. Contaminated biological agents
Third, interfere with the results of animal experiments.
Four. Threaten human health and safety.
Section III Health Observation of Experimental Animals
First, the contents and methods of health observation
Second, the experimental animal health observation matters needing attention
Section IV Transmission Route of Infectious Diseases in Laboratory Animals and Its Epidemic Prevention Measures
First, the basic link of the epidemic of infectious diseases in experimental animals
Second, the experimental animal health and epidemic prevention system
Section 5 Viral Diseases of Experimental Animals
First of all, mouse pox
Second, epidemic hemorrhagic fever.
Lymphocytic choroid plexus meningitis
Fourth, Sendai virus infection.
Verb (abbreviation of verb) mouse hepatitis
Six, rabbit hemorrhagic disease
Seven, rabies
Eight, canine distemper
Nine, canine parvovirus infection
Canine viral hepatitis
Eleven, monkey B virus infection
Section 6 Bacterial Diseases of Laboratory Animals
I. Salmonellosis
Second, Taze's disease.
Three, mycoplasma infection
Section 7 Parasitic Diseases of Experimental Animals
First of all, toxoplasmosis
Second, coccidiosis
Third, acariasis.
Section 8 Quality Control of Microbiology and Parasitology of Laboratory Animals
I. Requirements and standards for microbial monitoring of experimental animals
Two. Requirements and standards for parasitological monitoring of experimental animals
Three. Monitoring requirements and standards of pathogenic microorganisms in SPF chickens
Chapter IX Factors Affecting Experimental Animals and Animal Experiments
Section 1 Influence of Environmental Factors on the Results of Animal Experiments
I. Temperature
Second, humidity.
Three. Air flow, air flow speed and air exchange times
Fourth, noise.
Verb (abbreviation of verb) lighting equipment
Six, air cleanliness
Seven, harmful gases
Eight, the construction of animal facilities
Nine, animal facilities and equipment
X cages and bedding
Xi。 Feeding density
Twelve. Social factors and spheres of influence
The influence of experimental animal factors on animal experiments in the second quarter
I. Species
Second, nervous.
Third, gender.
Four. Age and weight
Verb (abbreviation for verb) physiological state
Health state of intransitive verbs
Effect of nutritional factors on animal experiment results
First, the impact of non-nutritional research
Second, the impact of nutrition research
Section IV Influence of Pathogenic Microbial Infection on Animal Experiments
First, the influence of virus infection on animal experiments
Second, the influence of bacterial infection on animal experiments
Third, the influence of parasitic infection on animal experiments
Section 5 the influence of technical factors on animal experiments
First, the choice of experimental animals
Second, the experimental season.
Third, the day and night process
Fourth, anesthesia
Five, surgical skills
Six, experimental drugs
Seven. Contradictory problem
Chapter X Basic Techniques of Animal Experiment
Section 1 Preparation before Animal Experiment
First, the serial number and marking of experimental animals
Second, the grouping of experimental animals
Third, the removal of the coat of experimental animals.
4. Grasping and fixing of experimental animals
Section 2 Anesthesia of Experimental Animals
First, the preparation before anesthesia
Second, commonly used anesthetics
Third, the commonly used anesthesia methods
Four, anesthesia monitoring and anesthesia accident rescue
Five, the influence of anesthesia on animal experiments
Section III Ways and Methods of Administration to Experimental Animals
First, oral administration
Two. Injection administration
Three, the experimental animal dosage and calculation method
Fourth, the tolerance of experimental animals once.
Section 4 Blood Collection and Body Fluid Collection of Experimental Animals
First, the blood collection method
Second, the collection of body fluids.
Section 5 Methods of Killing Experimental Animals
First, the lethal method of chemical drugs.
Second, the method of pulping
Three, air embolism method
Four, acute blood loss method
Five, beheading method
Section 6 corpse inspection and organ specimen collection and inspection methods
First, the external examination method of the corpse.
Second, the collection method of corpse viscera
Third, the inspection method of corpse organs
Four, the writing of autopsy records and autopsy reports
Section 7 Basic Operation Techniques of Animal Experimental Surgery
First, the preparation before animal experimental surgery
Second, the aseptic operation technology of surgical operation
Third, the basic operation technology of surgical operation
Four. Nursing and observation after animal experiment
Section 8 Harmless Treatment of Waste after Animal Experiment
I. Management of waste disposal
Second, the harmless treatment of sewage
Third, the harmless treatment of pollutants.
Four, the harmless treatment of animal carcasses
Chapter II XI Animal Experiment Management
Section 1 Quality Management of Animal Experiments
A, animal experiment quality management standards
Second, the basic content and responsibilities of quality management
Third, the organization and implementation of quality management
Four, the specific requirements of laboratory animal quality management
Five, animal laboratory documents and data management
Section 2 Selection Principles of Experimental Animals
First, the importance of the choice of experimental animals
Second, the principle of choosing experimental animals
Section 3 Design and Implementation of Animal Experiments
First, the quality requirements of laboratory personnel
Second, animal experiment design
Appendix I Comparison of Chinese and English Majors
Appendix II Laboratory Animal Websites at Home and Abroad
refer to