In 2003, Nepstar teamed up with Beijing Tongrentang (Group) and Beijing Capital to establish Beijing Tongrentang Commercial Investment Development Co., Ltd. to develop Tongrentang modern Chinese medicine pharmacy and make contributions to the health of Chinese medicine.
In September 2004, Goldman Sachs, the world's most famous investment bank, signed a direct investment agreement with Neptune Group, the major shareholder of Neptune Star, and Neptune Star became the first pharmaceutical retail enterprise in China to accept foreign direct investment.