Guo Songling defected in the winter of 1925. Zhang Xueliang once went to Huludao by warship to stop him from going north. Gu Ruiyu also got the nerve to accompany him. Because it was winter at that time, Zhang Xueliang suffered from insomnia all night because of defection. Staff Yang Yuting encouraged Zhang Xueliang to take opium to relieve his fatigue in recent days. As a result, Zhang Xueliang was unfortunately infected with opium addiction, and Gu Ruiyu cried and blamed himself. She was later criticized for this. This is also one of the internal reasons for her disagreement with Zhong.
1in the autumn of 926, Gu Ruiyu was criticized by the Zhang family for supporting Zhang Xueliang to smoke opium when Guo defected, so when Zhang Xueliang was stationed in Tianjin, she tried to persuade the rumbled to quit smoking to save her mistake. First, she asked the British doctor Heath to help her quit smoking, but it was easier to take drugs than to give them up. After several days and nights of tossing and turning, the result ended in failure. Gu Ruiyu mistakenly listened to the advice of a general of the Northeast Army, and invited Japanese doctor Jiro Yamada to assist in drug rehabilitation in Tianjin. Unexpectedly, this move made a bigger mistake. In order to get a considerable medical fee from Gu Ruiyu, Yamada used morphine to relieve Zhang Xueliang's pain of detoxification. As a result, although opium smoking was quit, it was even more difficult to quit because of morphine. Gu Ruiyu's kindness didn't get a good result, which made some people misunderstand her more deeply.
That winter, Gu Ruiyu went to Henan with Jong. Gu Ruiyu, who first arrived in Henan, was overworked for a few days and detoxified Zhang Xueliang, which was criticized by many people. There was a fire in his heart and he soon became seriously ill in Henan. Zhang Xueliang advised him to go back to Tianjin for medical treatment, but Gu Ruiyu insisted on staying because he was worried that Jong would be neglected in the war. In Henan, she treated diseases and took care of Zhang Xueliang's daily life until the end of the war. In recognition of Gu Ruiyu's contribution to the army, Zhang Xueliang bought a luxurious new house for Gu Ruiyu in Tianjin French Concession. In order to facilitate Gu Ruiyu to go to Beijing and go to the opera, he also bought Gu Ruiyu real estate and clothes in Beijing, which was undoubtedly the most harmonious period between Gu Ruiyu and Zhang Xueliang.