1. Pharmaceutical manufacturing enterprises: Pharmaceutical manufacturing enterprises should evaluate the quality and safety of the drugs they produce, and study and evaluate the possible adverse reactions of drugs. If adverse drug reactions are found, they should be reported to the regulatory authorities and health departments in time, and corresponding measures should be taken.
2. Medical institutions: Medical institutions should report the adverse reactions found in the process of drug follow-up, and record the occurrence of adverse reactions in patients' medical records, so as to facilitate doctors' treatment and follow-up of patients.
3. Patients and their families: Patients and their families should use drugs correctly under the guidance of doctors. Once an adverse reaction is found, it should be reported to the doctor in time and related questions should be consulted.
4. Regulatory departments and health departments: Regulatory departments and health departments are the main bodies of supervision and management of adverse drug reactions, and they have important responsibilities in the management of adverse drug reactions. Those who receive reports of adverse drug reactions shall promptly investigate and take corresponding measures.