According to the inquiry of the national medical insurance service platform, thiotepa has been included in the national medical insurance, which is a kind of medical insurance. Titepa injection can be reimbursed through medical insurance. Pharmaceutical companies are Shanghai Xudongpu Pharmaceutical Co., Ltd. and Heilongjiang Fuhe Pharmaceutical Group Co., Ltd..
Titepa is a synthetic antineoplastic agent and a representative of ethylenimine alkylating agent, which is effective for a variety of solid tumors. The principle of action is similar to nitrogen mustard, and the active alkyl group is an ethylenimine group produced in vivo, which is a cell cycle nonspecific drug. Experimental studies have proved that it has obvious inhibitory effect on various animal tumors and inhibits DNA synthesis.