1992, Dalian Municipal Committee issued the document "Dake Gaoxinfa (1992) 108", which marked the official approval of Dalian Totem Bioengineering Research Institute, whose predecessor was Dalian Totem Bioengineering Co., Ltd.;
In 2006, Dalian Totem Bioengineering Research Institute was officially renamed as Dalian Totem Bioengineering Co., Ltd., and has been specialized in the research of totem probiotic BF839 for several years, with national patents and 120 scientific research achievements. Its products have won the national "invention patent", "China Patent New Technology and New Products Expo Gold Award", "Second Edison World Invention Expo Special Honor Gold Award" and "World Excellent Patent (Technology) Transfer Certificate approved to enter the United States".
20 14 was awarded as "advanced unit of scientific and technological innovation in China in 20 14";
From June 2065438 to June 2005, the 28th generation of bacteria was successfully cultivated, reaching the international advanced level of bacteria, and the ability to inhibit tumors and reduce the toxic and side effects of radiotherapy and chemotherapy was greatly enhanced.