Shijiazhuang pharmaceutical group co., ltd
In the first half of 2004 alone, Unacon invested 654.38 billion yuan in R&D talent introduction, training and R&D funds, which was twice as much as 6543.8+ 0997 at the beginning of the year. Now it has 5,000 square meters of laboratories, 6 pilot workshops and a large number of advanced analytical and testing instruments and experimental equipment such as liquid chromatography-mass spectrometry, gas chromatography, high performance liquid chromatography, infrared chromatography, scanning electron microscope, high performance capillary electrophoresis, atomic absorption spectrophotometer, thermal analyzer, chromatographic system, electrophoresis system, low-temperature refrigerator, low-temperature high-speed centrifuge, freeze dryer and centrifugal granulator, which has created a good hardware environment for the development of new drugs and technologies. The number of R&D technicians in the Technology Center has reached 7 1 person, and a strong R&D team has been established. In recent years, * * * 8 new varieties have obtained clinical approval numbers, 5 products have obtained drug approval numbers, 2 products have obtained new drug certificates, and 140 varieties are under development.
Unacon invested/kloc-0.6 billion yuan in technical progress and innovation, and adopted advanced technologies such as information technology, genetic engineering, enzyme engineering, nano-membrane separation technology and chromatographic purification technology to transform traditional industries, and launched a large number of new technical projects such as semi-synthetic antibiotics, 7-ACA, cephalosporins, vitamin C derivatives and soybean base. Among them, the total production capacity of enzymatic 7-ACA production line is 1.600 tons/year, accounting for more than 32% of the international market share. It is one of the most advanced 7-ACA production lines in the world.
In addition, based on the original cephalosporin products, products such as cefaclor and cefepime were further developed. After successful production expansion and transformation, vitamin C has achieved technological breakthroughs such as two-step fermentation, new resin exchange technology and nano-membrane separation. At the same time, deep-processed products such as sodium vitamin C and calcium vitamin C have been further developed.
Practice has proved that the three-level R&D system has many advantages: it can fully mobilize the enthusiasm of the group to participate in and invest in R&D from subsidiaries, production workshop departments and levels; Effectively solve the problem that technological innovation is out of touch with production and marketing; Make the research and development work meet the needs of the group's short, medium and long-term development at the same time; Strengthened the reserve force of the group's R&D talents.