What is capillary permeability?

Capillary permeability: In view of the fact that white blood cells and antibodies, the two main components against pathogenic microorganisms, are transported by blood, hemodynamic changes, vascular permeability increase and white blood cell exudation are very obvious during acute inflammation. Results protein-rich exudate, fibrin and white blood cells accumulated in the extravascular space of the injured site.

Excessive exudation will affect organ function and oppress neighboring organs. For example, the accumulation of exudate in lung cells will affect ventilation function, pericardium and pleural effusion will compress the heart and lungs, and severe laryngeal edema will cause suffocation, and so on.

Extended data:

The maintenance of microcirculation vascular permeability in microcirculation mode mainly depends on the integrity of endothelial cells. In the process of inflammation, the following mechanisms can cause the increase of vascular permeability.

Endothelial cell contraction Inflammatory mediators such as histamine and bradykinin can quickly cause endothelial cell contraction after binding with endothelial cell receptors, resulting in the formation of gaps between endothelial cells with a width of about 0.5 ~1.0 μ m.

Baidu Encyclopedia-Increased pleural capillary permeability