Lenalidomide, also known as fosfomycin and rellidomide, is one of the core varieties of new alkali organisms in the United States. Lenalidomide is an immunomodulatory preparation for anti-tumor cell proliferation and an anticancer drug for treating multiple myeloma, and its curative effect is quite remarkable. The FDA first approved lenalidomide for the treatment of myelodysplastic syndrome in February 2005, and then added the indications for the treatment of relapsed and refractory multiple myeloma in 2006, mantle cell lymphoma in 20 13 and multiple myeloma in 20 15. At present, there are two versions of Indian lenalidomide and domestic lenalidomide on the market.
What is the domestic situation of lenalidomide?
As we all know, lenalidomide in India comes from the imitation version in India. India's generic pharmaceutical industry has always been relatively developed, and it is not restricted by patents, and it also needs the support of the Indian government. Therefore, the Indian imitation version of lenalidomide (rifamycin) has the same composition and curative effect as the original drug, and its price is relatively low. Then how about coming to Nadamine for domestic production? According to Weihekang Medical, 20 17 165438 Shuanglu pharmaceutical generic drug lenalidomide was listed for the first time, and some people called it Shuanglu domestic lenalidomide. According to statistics, in 20 18 (Ruifumei), the project achievement of lenalidomide generic drug was about 33 million. It is predicted that the annual establishment performance will exceed 1 100 million yuan, close to10.20 billion yuan. As the second domestic generic drug of lenalidomide, Zheng Da Tianqing Anxian is also expected.
Does the domestic listing of lenalidomide affect patients?
For patients, domestic lenalidomide may be more convenient, depending on whether the price is different from the original drug. It is understood that patients spend 59,000 yuan per month to buy original lenalidomide, and the annual drug cost is nearly 700,000 yuan. Since 20 17 original research drug lenalidomide entered the medical insurance, although the price of lenalidomide has dropped obviously, the total price is still relatively expensive, which is unbearable for patients. Under the joint pressure of cavendish and Shuanglu Pharmaceutical Co., Ltd., American Xinji Company finally agreed to slightly lower the price of naturamide in the future. The relevant person in charge said that the price of domestic lenalidomide has not yet been finalized, but it will be greatly reduced to help patients alleviate economic pressure.
What side effects does lenalidomide have?
According to relevant clinical experience, lenalidomide has relatively few side effects. Common side effects include itching, cough, rash, nausea and diarrhea, fever and headache, joint pain and other symptoms. Some patients may also have peripheral edema, and some patients may have thrombocytopenia. The degree of side effects varies with the patient's constitution, and patients need to pay attention to the details of medication.