What does TBA mean?

Thiobarbituric acid (TBA) method: The principle of TBA method is that malondialdehyde (MDA), one of the degradation products of lipid peroxidation, can be colored by thiobarbituric acid. Cholesterol is a bile acid directly synthesized by hepatocytes, including cholic acid, chenodeoxycholic acid and corresponding conjugated bile acids.

TBA method is a very simple method, which can be carried out in general laboratories. This method has a good correlation with fluorescence method and chemiluminescence method, but its deficiency is poor sensitivity. Some factors need to be controlled, such as mitochondrial pollution and iron ions in the sample.

Extended data:

The colorimetric determination of thiobarbituric acid (TBA) at 520nm can detect the change of malondialdehyde relative content, so as to understand the situation of biofilm peroxidation. TBA method is a very simple method, which can be carried out in general laboratories.

This method has a good correlation with fluorescence method and chemiluminescence method, but its deficiency is poor sensitivity. Some factors need to be controlled, such as mitochondrial pollution and iron ions in the sample.

References:

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