Pharmacological action This product can obviously inhibit the production of interleukin l(IL 1) by macrophages, and has anti-inflammatory and anti-rheumatic effects. Methylene diphosphate (MDP) in this product can reduce the damage of collagenase to synovial tissue of joints by integrating metal ions, and the trace element technetium can scavenge free radicals in human body, protect the activity of superoxide dismutase (SOD) and regulate the autoimmune function of human body. This product can also inhibit the synthesis of prostaglandin and has obvious analgesic effect. This product has obvious targeting to bones and joints, is safe and effective, and the dosage is small.
Indications of rheumatoid arthritis.
Usage and Dosage Before use, under aseptic operation conditions, pour 5ml of Agent A into the freeze-dried bottle of Agent B, shake well to dissolve the freeze-dried substance, and let stand 5ml of N, iv, qd for 20 times, 1 course of treatment. According to the needs of the disease, the dosage can be appropriately increased and the course of treatment can be prolonged.
Under the condition of normal dose, the adverse drug reactions are few and mild. Occasionally rash, local redness and swelling after injection, systemic edema, anorexia, and increased menstrual flow. Stop taking medicine when it is serious.
Contraindications allergic constitution, hypotension and severe hepatic and renal insufficiency are prohibited. Use with caution in patients with cardiac insufficiency.
Note: If the injection changes color or precipitates, the injection should be stopped.
Specification and package: Agent A: 5mL per bottle (containing artificial trace element technetium [99Tc]0.05ug), and Agent B: 5.5mg per bottle (containing MDP5mg and SnCL20.5mg).
Reference price retail price: 75.oo yuan.
Storage conditions are sealed, and dose B is stored at 2-8℃ in the dark. The validity period is 1.5 years.
Manufacturer Chengdu Yunke Pharmaceutical Co., Ltd. (formerly Chengdu Isotope Application Institute of China Nuclear Power Research and Design Institute)
Factory Address: No.28, South Third Section, First Ring Road, Chengdu
The approval number is National Medicine Zhunzi X200002 18.